Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot (Negative)

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

1.0 mg/ml

View all BCCIP Antibodies »

Product Specifications

Immunogen

The immunogen recognized by this antibody maps to a region between residue 300 and 350 of human BRCA2 and CDKN1A interacting protein using the numbering given in entry NP_510868.1 (GeneID 56647).

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCCIP Antibody

Immunohistochemistry: BCCIP Antibody [NBP1-22994]

Immunohistochemistry: BCCIP Antibody [NBP1-22994]

Immunohistochemistry: BCCIP Antibody [NBP1-22994] - FPE section of human colon carcinoma. Antibody used at a dilution of 1:250. Detection: DAB staining using Immunohistochemistry Accessory Kit.
Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994]

Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994]

Immunohistochemistry-Paraffin: BCCIP Antibody [NBP1-22994] - Human prostate carcinoma. Antibody used at a dilution of 1:1000 (1ug/ml).
Immunoprecipitation: BCCIP Antibody [NBP1-22994]

Immunoprecipitation: BCCIP Antibody [NBP1-22994]

Immunoprecipitation: BCCIP Antibody [NBP1-22994] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-BCCIP antibody used for IP at 3 mcg/mg lysate. BCCIP was also immunoprecipitated by rabbit anti- BCCIP antibody NBP1-22993, which recognizes an upstream epitope.

Applications for BCCIP Antibody

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Immunoprecipitation

2-5 ug/mg lysate
Application Notes
It is not recommended for western analysis.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris-Citrate/Phosphate (pH 7.0 - 8.0)

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: BCCIP

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Alternate Names

BCCIPalpha, BRCA2 and CDKN1A interacting protein, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, cdk inhibitor p21 binding protein, P21- and CDK-associated protein 1, Protein TOK-1, TOK-1, TOK-1alpha, TOK1BCCIPbeta, TOK-1beta

Entrez Gene IDs

56647 (Human)

Gene Symbol

BCCIP

UniProt

NP_510868.1 (Human)

Additional BCCIP Products

Product Documents for BCCIP Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BCCIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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