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BCCIP Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-55218

Novus Biologicals, part of Bio-Techne
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NBP2-55218
NBP2-55218-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for BCCIP Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: ALPMYQQLQKELAGAHRTNKPCGKCYFYLLISKTFVEAGKNNSKKKPSNKKKAALMFANAEEEFFYEEQGKPEVLGGPDTRRGLEPVPIQHNGGSR

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCCIP Antibody

Immunocytochemistry/ Immunofluorescence: BCCIP Antibody [NBP2-55218]

Immunocytochemistry/ Immunofluorescence: BCCIP Antibody [NBP2-55218]

Immunocytochemistry/Immunofluorescence: BCCIP Antibody [NBP2-55218] - Staining of human cell line HEK 293 shows localization to nucleoplasm & cytosol.

Applications for BCCIP Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml
Application Notes
Immunocytochemistry/Immunofluorescence Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BCCIP

BCCIP (BRCA2 and CDKN1A interacting protein) was isolated as a BRCA2 and p21 interacting protein. Downregulation of BCCIP results in chromosome instability and incomplete cytokinesis indicating a role in DNA damage. Additionally, BCCIP is critical for BRCA2- and Rad51-dependent homologous recombinational repair.

Alternate Names

BCCIPalpha, BRCA2 and CDKN1A interacting protein, BRCA2 and CDKN1A-interacting protein, BRCA2 and Cip1/p21 interacting protein, cdk inhibitor p21 binding protein, P21- and CDK-associated protein 1, Protein TOK-1, TOK-1, TOK-1alpha, TOK1BCCIPbeta, TOK-1beta

Gene Symbol

BCCIP

Additional BCCIP Products

Product Documents for BCCIP Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BCCIP Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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