Bcl G Antibody (S06-3D8)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-19984

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-19984-100ul
NBP3-19984-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # S06-3D8

Concentration

0.3 mg/ml

View all Bcl G Antibodies »

Product Summary for Bcl G Antibody (S06-3D8)

Immunogen

Recombinant protein of human Bcl G (Uniprot # Q9BZR8)

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

43 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Bcl G Antibody (S06-3D8)

Western Blot: Bcl G Antibody (S06-3D8) [NBP3-19984]

Western Blot: Bcl G Antibody (S06-3D8) [NBP3-19984]

Western Blot: Bcl G Antibody (S06-3D8) [NBP3-19984] - Western blot detection of Bcl G in Hela, A549, HL-60, U251, U87-MG cell lysates using NBP3-19984 (1:1000 diluted). Predicted band size: 37kDa. Observed band size: 43kDa.
Immunocytochemistry/ Immunofluorescence: Bcl G Antibody (S06-3D8) [NBP3-19984]

Immunocytochemistry/ Immunofluorescence: Bcl G Antibody (S06-3D8) [NBP3-19984]

Immunocytochemistry/Immunofluorescence: Bcl G Antibody (S06-3D8) [NBP3-19984] - Immunocytochemistry of Bcl G (green) in hela using NBP3-19984 at dilution 1/50, and DAPI (blue)

Applications for Bcl G Antibody (S06-3D8)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1/50

Western Blot

1/1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.05% BSA

Preservative

0.01% Sodium Azide

Concentration

0.3 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Bcl G

Members in the Bcl-2 family are critical regulators of apoptosis by either inhibiting or promoting cell death. Bcl-2 homology 3 (BH3) domain is a potent death domain. BH3 domain containing pro-apoptotic proteins, including Bad, Bax, Bid, Bik, and Hrk, form a growing subclass of the Bcl-2 family. A novel BH3 domain containing protein was recently identified and designated Bcl-G. The mRNA of Bcl-G encodes 2 isoforms, Bcl-GL, which is widely expressed in multiple tissues, and Bcl-GS, which is only found in testis. The Bcl-GS protein is predominantly localized to cytoplasmic organelles whereas Bcl-GL was distributed throughout the cytosol. Overexpression of either protein induced apoptosis, although Bcl-GS was far more potent than Bcl-GS. Apoptosis induction was dependent on the BH3 domain and could be suppressed by co-expression with the anti-apoptotic Bcl-XL protein.

Alternate Names

apoptosis facilitator Bcl-2-like protein 14, Apoptosis regulator Bcl-G, Bcl2-L-14, BCL2-like 14 (apoptosis facilitator), BCL-G, BCLGbcl2-L-14

Gene Symbol

BCL2L14

Additional Bcl G Products

Product Documents for Bcl G Antibody (S06-3D8)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Bcl G Antibody (S06-3D8)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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