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BCL11B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-33549

Novus Biologicals, part of Bio-Techne
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NBP2-33549
NBP2-33549-25ul

Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human, Mouse

Cited:

Mouse

Predicted:

Rat (98%). Backed by our 100% Guarantee.

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: QGNPQHLSQRELITPEADHVEAAILEEDEGLEIEEPSGLGLMVGGPDPDLLTCG

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for BCL11B Antibody

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549]

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549]

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Analysis in human skin and pancreas tissues. Corresponding RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: BCL11B Antibody [NBP2-33549]

Immunocytochemistry/ Immunofluorescence: BCL11B Antibody [NBP2-33549]

Immunocytochemistry/Immunofluorescence: BCL11B Antibody [NBP2-33549] - Staining of human cell line MCF7 shows localization to nucleus & nucleoli fibrillar center. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549]

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549]

Immunohistochemistry-Paraffin: BCL11B Antibody [NBP2-33549] - Staining of human cerebral cortex shows weak to moderate nuclear positivity in neurons.

Applications for BCL11B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BCL11B

The BCL11B gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. The specific function of this gene has not yet been determined. Two alternatively spliced transcript

Alternate Names

B-cell CLL/lymphoma 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein, B-cell lymphoma/leukaemia 11B, B-cell lymphoma/leukemia 11B, BCL-11B, BCL11B/TRDC fusion, COUP-TF-interacting protein 2, CTIP-2, CTIP2ZNF856B, hRit1, hRIT1-alpha, Radiation-induced tumor suppressor gene 1 protein, RIT1, zinc finger protein hRit1 alpha

Gene Symbol

BCL11B

UniProt

Additional BCL11B Products

Product Documents for BCL11B Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BCL11B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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