BCL2L10 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31681

Novus Biologicals, part of Bio-Techne
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NBP1-31681
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BCL2L10 Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human BCL2L10. The exact sequence is proprietary.

Localization

Mitochondrion, Nucleus membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

22 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BCL2L10 Antibody

Immunocytochemistry/ Immunofluorescence: BCL2L10 Antibody [NBP1-31681]

Immunocytochemistry/ Immunofluorescence: BCL2L10 Antibody [NBP1-31681]

Immunocytochemistry/Immunofluorescence: BCL2L10 Antibody [NBP1-31681] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.
Immunohistochemistry-Paraffin: BCL2L10 Antibody [NBP1-31681]

Immunohistochemistry-Paraffin: BCL2L10 Antibody [NBP1-31681]

Immunohistochemistry-Paraffin: BCL2L10 Antibody [NBP1-31681] - Paraffin-embedded A549 Xenograft, using antibody at 1:100 dilution.
BCL2L10 Antibody

Western Blot: BCL2L10 Antibody [NBP1-31681] -

Western Blot: BCL2L10 Antibody [NBP1-31681] -Various whole cell extracts (30 ug) were separated by 12% SDS-PAGE, and the membrane was blotted with BCL2L10 antibody [N2C2], Internal diluted at 1:1000. The HRP-conjugated anti-rabbit IgG antibody (NBP2-19301) was used to detect the primary antibody.

Applications for BCL2L10 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Immunohistochemistry

1:100-1:1000

Immunohistochemistry-Paraffin

1:100-1:1000

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.025% Proclin 300

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BCL2L10

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The protein encoded by this gene contains conserved BH4, BH1 and BH2 domains. This protein can interact with other members of BCL-2 protein family including BCL2, BCL2L1/BCL-X(L), and BAX. Overexpression of this gene has been shown to suppress cell apoptosis possibly through the prevention of cytochrome C release from the mitochondria, and thus activating caspase-3 activation. The mouse counterpart of this protein is found to interact with Apaf1 and forms a protein complex with Caspase 9, which suggests the involvement of this protein in APAF1 and CASPASE 9 related apoptotic pathway.

Long Name

Bcl-2-like protein 10

Alternate Names

BCL-B, Bcl2-L-10, BCLB, BOO, DIVA

Entrez Gene IDs

10017 (Human)

Gene Symbol

BCL2L10

UniProt

Q9HD36 (Human)

Additional BCL2L10 Products

Product Documents for BCL2L10 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BCL2L10 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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