Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # B31.15

Format

BSA Free

Concentration

1.0 mg/ml

View all Beta-endorphin Antibodies »

Product Specifications

Immunogen

Human beta Endorphin (full length native protein).

Specificity

The antibody B31.15 reacts with human beta Endorphin, an endogenous opiate derived from ACTH gene. ACTH (Corticotropin; human 39 aa) is synthesized by the anterior pituitary gland and stimulates the adrenal cortex; 6 hormones are derived from one ACTH gene: ACTH, lipotropin, alpha-MSH, beta-MSH, endorphin, and one other.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Beta-endorphin Antibody (B31.15) - BSA Free

Immunohistochemistry: Beta-endorphin Antibody (B31.15) - BSA Free [NB500-414]

Immunohistochemistry: Beta-endorphin Antibody (B31.15) - BSA Free [NB500-414]

Immunohistochemistry: Beta-endorphin Antibody (B31.15) [NB500-414] - Staining of human pituitary gland (frozen sections) with anti-human Beta-endorphin (B31.15).

Applications for Beta-endorphin Antibody (B31.15) - BSA Free

Application
Recommended Usage

Immunohistochemistry

10-20 ug/ml

Immunohistochemistry-Frozen

1:200

Immunohistochemistry-Paraffin

10 ug/ml
Application Notes
Purity is > 95% (by SDS-PAGE). Immunohistochemistry-Paraffin sections: Staining technique: Standard ABC technique (DAB+) Pretreatment: Heat retrieval (microwave oven) Incubation: overnight at 4oC

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

PBS (pH 7.4)

Format

BSA Free

Preservative

0.09% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: Beta-endorphin

Beta-endorphin is an endogenous opioid peptide neurotransmitter found in the neurons of both the central and peripheral nervous system. Beta-endorphin is a peptide, 31 amino acids long, resulting from processing of the precursor pro-opiomelanocortin (POMC). beta-endorphin is found in neurons of the hypothalamus as well as the pituitary gland. It is an agonist of the opioid receptors, with evidence suggesting that it serves as the endogenous ligand of the u-opioid receptor, the same receptor to which the chemicals extracted from opium, such as morphine and codeine, have their analgesic and addictive effects

Alternate Names

ACTH, adrenocorticotropic hormone, adrenocorticotropin, alpha-melanocyte-stimulating hormone, alpha-MSH, beta-endorphin, beta-LPH, beta-melanocyte-stimulating hormone, beta-MSH, CLIP, corticotropin-like intermediary peptide, Corticotropin-lipotropin, gamma-LPH, gamma-MSH, lipotropin beta, lipotropin gamma, LPH, melanotropin alpha, melanotropin beta, melanotropin gamma, met-enkephalin, MSH, NPP, POC, pro-ACTH-endorphin, proopiomelanocortin, pro-opiomelanocortin, proopiomelanocortin preproprotein

Entrez Gene IDs

5443 (Human)

Gene Symbol

POMC

UniProt

P01189

Additional Beta-endorphin Products

Product Documents for Beta-endorphin Antibody (B31.15) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Beta-endorphin Antibody (B31.15) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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