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BMI-1 Antibody (LLBmi1-1) [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-96140C

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse

Applications

Chromatin Immunoprecipitation (ChIP), Flow (Intracellular), Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunoprecipitation, Western Blot

Label

DyLight 650 (Excitation = 652 nm, Emission = 672 nm)

Antibody Source

Monoclonal Mouse IgG2b Kappa Clone # LLBmi1-1

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for BMI-1 Antibody (LLBmi1-1) [DyLight 650]

Immunogen

Human Bmi1 protein [Swiss-Prot# P35226]

Localization

Nucleus. Cytoplasm.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2b Kappa

Applications for BMI-1 Antibody (LLBmi1-1) [DyLight 650]

Application
Recommended Usage

Chromatin Immunoprecipitation (ChIP)

Optimal dilutions of this antibody should be experimentally determined.

Flow (Intracellular)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: BMI-1

Bmi1 is a member of the polycomb group (PcG) multiprotein PRC1 complex which functions to control axial skeleton development through Hox gene repression. Bmi1 plays an important role in repressing the transcription of the p16Ink4a and p19Arf genes and is required to maintain the proliferative and self-renewal properties of adult hematopoietic and neural stem cells. Bmi1 is an oncogene whose overexpression has been associated with many types of human tumors, including those in breast, colorectal, prostate, and non-small cell lung cancers. As seen in many recent publications, Bmi1 antibodies can serve as useful research tools to study Bmi1 and its effect on tumor proliferation and tumorigenesis.

Long Name

B Lymphoma Mo-MLV Insertion Region 1

Alternate Names

BMI1, PCGF4, RNF51

Gene Symbol

BMI1

Additional BMI-1 Products

Product Documents for BMI-1 Antibody (LLBmi1-1) [DyLight 650]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for BMI-1 Antibody (LLBmi1-1) [DyLight 650]



DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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