BMP-8a Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-31168

Novus Biologicals, part of Bio-Techne
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NBP1-31168
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Key Product Details

Species Reactivity

Validated:

Human, Mouse

Predicted:

Rat (100%). Backed by our 100% Guarantee.

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all BMP-8a Antibodies »

Product Specifications

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human BMP-8a. The exact sequence is proprietary.

Localization

Secreted

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

45 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for BMP-8a Antibody

Western Blot: BMP-8a Antibody [NBP1-31168]

Western Blot: BMP-8a Antibody [NBP1-31168]

Western Blot: BMP-8a Antibody [NBP1-31168] - Sample(30 ug of whole cell lysate)A:H1299B:Raji 7.5% SDS PAGE, antibody diluted at 1:500.
Immunocytochemistry/ Immunofluorescence: BMP-8a Antibody [NBP1-31168]

Immunocytochemistry/ Immunofluorescence: BMP-8a Antibody [NBP1-31168]

Immunocytochemistry/Immunofluorescence: BMP-8a Antibody [NBP1-31168] - Sample: U2OS cells were fixed in 4% paraformaldehyde at RT for 15 min. Green: BMP8A protein stained by BMP8A antibody [C3], C-term diluted at 1:500. Blue: Hoechst 33342 staining. Scale bar = 10 um.
Immunocytochemistry/ Immunofluorescence: BMP-8a Antibody [NBP1-31168]

Immunocytochemistry/ Immunofluorescence: BMP-8a Antibody [NBP1-31168]

Immunocytochemistry/Immunofluorescence: BMP-8a Antibody [NBP1-31168] - Paraformaldehyde-fixed mouse ESC D3, using antibody at 1:200 dilution.

Applications for BMP-8a Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

1:100-1:1000

Western Blot

1:500-1:3000

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

0.1M Tris (pH 7), 0.1M Glycine, 10% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: BMP-8a

Bone morphogenic proteins (BMPs) are members of the TGFbeta superfamily. BMPs are involved in the induction of cartilage and bone formation. In vivo studies have shown that BMP-2 (also designated BMP-2A) and BMP-3 can independently induce cartilage formation. Smad3 association with the TGFbeta receptor complex and Smad1 translocation to the nucleus are observed after the addition of BMP-4 (also designated BMP-2B), suggesting that BMP-4 may play a role in activation of the Smad pathway. BMP-5, BMP-6 and BMP-7 all share high sequence homology with BMP-2, indicating that they each may be able to induce cartilage formation. BMP-8 is thought to be involved in early development, as detectable expression has not been found in adult organs.Two BMP-8 proteins exist, namely BMP-8A and BMP-8B (also designated OP-2), and are encoded by two distinct genes.

Long Name

Bone Morphogenetic Protein 8a

Alternate Names

Op2, Osteogenic Protein 2

Gene Symbol

BMP8A

Additional BMP-8a Products

Product Documents for BMP-8a Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for BMP-8a Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

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