BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12031

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2 Clone # MM0055-3E12

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all BMPR-IB/ALK-6 Antibodies »

Product Specifications

Immunogen

Human recombinant BMPR-IB/ALK-6 (extracellular domain)

Specificity

In direct ELISAs and Western blots, 100% good cross-reactivity with recombinant mouse BMPR-IB, but no cross-reactivity with recombinant human and mouse BMPR-IA is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2

Scientific Data Images for BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free

Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free [NBP2-12031]

Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free [NBP2-12031]

Immunohistochemistry-Paraffin: BMPR-IB/ALK-6 Antibody (MM0055-3E12) [NBP2-12031] - Human placenta (formalin fixed and paraffin embedded) section is subjected to IHC using MM0055-3E12

Applications for BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free

Application
Recommended Usage

Immunohistochemistry

1:50-1:200

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:100-1:1000

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.2 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: BMPR-IB/ALK-6

BMPR1B encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension.

Long Name

Bone Morphogenetic Protein Receptor IB

Alternate Names

ALK-6, BMPR1B, BMPRIB, CDw293

Gene Symbol

BMPR1B

UniProt

O00238

Additional BMPR-IB/ALK-6 Products

Product Documents for BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

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Product Specific Notices for BMPR-IB/ALK-6 Antibody (MM0055-3E12) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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