BP1 Antibody [Janelia Fluor® 635]
Novus Biologicals, part of Bio-Techne | Catalog # NB100-481JF635
Conjugate
Catalog #
Key Product Details
Species Reactivity
Human
Applications
Chromatin Immunoprecipitation (ChIP), Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Immunoprecipitation, Western Blot
Label
Janelia Fluor 635
Antibody Source
Polyclonal Rabbit IgG
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Specifications
Immunogen
A synthetic peptide made specifically to the human BP1 protein sequence (between residues 1-60) [UniProt# Q92988].
Reactivity Notes
Immunogen displays the following percentage of sequence identity for non-tested species: mouse (82%).
Localization
Nuclear.
Specificity
This is specific for human BP1 (DLX4 variant 1). Berg PE, Kirolikar S. DLX4 (distal-less homeobox 4). Atlas Genet Cytogenet Oncol Haematol. January 2011. URL : http://AtlasGeneticsOncology.org/Genes/DLX4ID49827ch17q21.html
Clonality
Polyclonal
Host
Rabbit
Isotype
IgG
Applications for BP1 Antibody [Janelia Fluor® 635]
Application
Recommended Usage
Chromatin Immunoprecipitation (ChIP)
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Frozen
Optimal dilutions of this antibody should be experimentally determined.
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Immunoprecipitation
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Immunogen affinity purified
Formulation
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: BP1
BP1 has been shown to be activated in 80% of invasive ductal breast tumors and is associated with breast cancer progression. BP1 is also expressed in the bone marrows of 63% of acute myeloid leukemia (AML) patients. In addition, BP1 plays a role in globin gene regulation by repressing the beta-globin gene. Therefore, BP1 antibodies are useful tools for various cancer studies.
Alternate Names
Beta protein 1, BP1distal-less homeo box 7, distal-less homeobox 4, DLX7distal-less homeo box 9, DLX8DLX9, homeobox protein DLX-4, Homeobox protein DLX-7, Homeobox protein DLX-8
Gene Symbol
DLX4
Additional BP1 Products
Product Documents for BP1 Antibody [Janelia Fluor® 635]
Product Specific Notices for BP1 Antibody [Janelia Fluor® 635]
Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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