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Bradykinin RB2/BDKRB2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-14351

Novus Biologicals, part of Bio-Techne
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NBP2-14351
NBP2-14351-25ul

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to the amino acids: FSPWKISMFLSVREDSVPTTASFSADMLNVTLQGPTLNGTFAQSKCPQVEWLGWLNTIQP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Bradykinin RB2/BDKRB2 Antibody

Bradykinin RB2/BDKRB2 Antibody

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] -

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] -Staining of human cerebral cortex shows strong positivity in neuronal processes.
Bradykinin RB2/BDKRB2 Antibody

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] -

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] - Staining of human stomach shows strong membranous positivity in glandular cells.
Bradykinin RB2/BDKRB2 Antibody

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] -

Immunohistochemistry-Paraffin: Bradykinin RB2/BDKRB2 Antibody [NBP2-14351] - Staining of human skeletal muscle shows no positivity myocytes as expected.

Applications for Bradykinin RB2/BDKRB2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

Reported in scientific literature (PMID 28757212).

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Bradykinin RB2/BDKRB2

BDKRB2, or Bradykinin Receptor B2, mediates smooth muscle contraction, induces relaxation of arteries, and stimulates diuresis. In addition, bradykinin B2 receptor has been implicated in inflammation and response to pain. This receptor is encoded by a single-copy gene. Two variants are produced by alternate start codons. BDKRB2/Bradykinin B2 receptor expression has been reported in blood, brain, eye, kidney, liver, lung, prostate, skin, small intestine, synovium, uterus, and vessel. ESTs have been isolated from colon, connective tissue, heart, heart/melanocyte/uterus, kidney, lung, placenta, and thyroid libraries.

Long Name

Bradykinin Receptor B2

Alternate Names

B2R, BDKRB2, BKR2, BradykininRB2, BRB2

Gene Symbol

BDKRB2

Additional Bradykinin RB2/BDKRB2 Products

Product Documents for Bradykinin RB2/BDKRB2 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Bradykinin RB2/BDKRB2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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