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C1QB Antibody (C1QB/2961)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79786

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # C1QB/2961

Concentration

0.2 mg/ml

Product Summary for C1QB Antibody (C1QB/2961)

Immunogen

Recombinant fragment (around aa 41-188) of human C1QB protein (exact sequence is proprietary) (Uniprot: P02746)

Localization

Cytoplasmic, Cell Surface

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Description

200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP2-79920)

Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80C.

Scientific Data Images for C1QB Antibody (C1QB/2961)

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) [NBP2-79786]

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) [NBP2-79786]

Immunohistochemistry-Paraffin: C1QB Antibody (C1QB/2961) [NBP2-79786] - Formalin-fixed, paraffin-embedded human Hepatocellular Carcinoma stained with C1QB Antibody (C1QB/2961).
Protein Array: C1QB Antibody (C1QB/2961) [NBP2-79786]

Protein Array: C1QB Antibody (C1QB/2961) [NBP2-79786]

Protein Array: C1QB Antibody (C1QB/2961) [NBP2-79786] - Analysis of Protein Array containing more than 19,000 full-length human proteins using C1QB Antibody (C1QB/2961). Z- and S- Score: The Z-score represents the strength of a signal that a monoclonal antibody (Monoclonal Antibody) (in combination with a fluorescently-tagged anti-IgG secondary antibody) produces when binding to a particular protein on the HuProt(TM) array. Z-scores are described in units of standard deviations (SD's) above the mean value of all signals generated on that array. If targets on HuProt(TM) are arranged in descending order of the Z-score, the S-score is the difference (also in units of SD's) between the Z-score. S-score therefore represents the relative target specificity of a Monoclonal Antibody to its intended target. A Monoclonal Antibody is considered to specific to its intended target, if the Monoclonal Antibody has an S-score of at least 2.5

Applications for C1QB Antibody (C1QB/2961)

Application
Recommended Usage

Immunohistochemistry

1-2 ug/ml

Immunohistochemistry-Paraffin

1-2 ug/ml
Application Notes
Immunohistochemistry (Formalin-fixed): 1-2ug/ml for 30 minutes at RT. Staining of formalin-fixed tissues requires heating tissue sections in 10mM Tris with 1mM EDTA, pH 9.0, for 45 min at 95C followed by cooling at RT for 20 minutes.
Optimal dilution for a specific application should be determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

10 mM PBS with 0.05% BSA

Preservative

0.05% Sodium Azide

Concentration

0.2 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C.

Background: C1QB

C1QB encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the B-chain polypeptide of human complement subcomponent C1q [provided by RefSeq]

Alternate Names

B chain, complement C1q subcomponent subunit B, complement component 1, q subcomponent, B chain, complement subcomponent C1q chain B, q subcomponent, beta polypeptide

Gene Symbol

C1QB

UniProt

Additional C1QB Products

Product Documents for C1QB Antibody (C1QB/2961)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for C1QB Antibody (C1QB/2961)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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