C1qTNF1/CTRP1 Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-76626

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Rat

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunocytochemistry/ Immunofluorescence

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CTRP1/C1qTNF1 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid synthetic peptide from near the amino-terminus of human CTRP1. The immunogen is located within amino acids 40 - 90 of CTRP1. Amino Acid Squence: ERAEEQHEKYRPSQD

Specificity

These proteins are often highly modified post-translationally and migrate in SDS-PAGE at positions other than their predicted size.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for C1qTNF1/CTRP1 Antibody - BSA Free

Western Blot: C1qTNF1/CTRP1 AntibodyBSA Free [NBP1-76626]

Western Blot: C1qTNF1/CTRP1 AntibodyBSA Free [NBP1-76626]

Western Blot: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Analysis of CTRP1 in human kidney cell lysate with CTRP1 (NT) antibody using NBP1-76626 at (A) 1 and (B) 2 ug/ml.
Immunohistochemistry-Paraffin: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626]

Immunohistochemistry-Paraffin: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626]

Immunohistochemistry-Paraffin: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Human kidney tissue with CTRP1 antibody at 10 ug/ml.
Immunofluorescence: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626]

Immunofluorescence: C1qTNF1/CTRP1 Antibody - BSA Free [NBP1-76626]

Immunofluorescence: C1qTNF1/CTRP1 Antibody [NBP1-76626] - Immunofluorescence of CTRP1 in Human Kidney cells with CTRP1 antibody at 20 ug/mL.

Applications for C1qTNF1/CTRP1 Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

10 ug/ml

Immunohistochemistry-Paraffin

10 ug/ml

Western Blot

1-2 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID:34422821).
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CTRP1/C1qTNF1

Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines. One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-alpha-related proteins (CTRPs) 1-7. Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues. These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene. In obese (ob/ob) mice, RT-PCR analysis showed that mCTRP1 transcripts are seen at substantially higher levels in adipose tissues compared to those of normal mice.

Long Name

C1q And Tumor Necrosis Factor Related Protein 1

Alternate Names

C1qTNF1, ZSIG37

Gene Symbol

C1QTNF1

UniProt

NP_940995 (Human)

Additional CTRP1/C1qTNF1 Products

Product Documents for C1qTNF1/CTRP1 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for C1qTNF1/CTRP1 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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