CTRP1/C1qTNF1: cDNA Clones

C1qTNF proteins constitute a highly conserved family of Acrp30/Adiponectin paralogs that share a modular organization comprising an N-terminal signal peptide, a short variable region, a collagenous domain, and a C-terminal globular domain. C1qTNF proteins are predicted to have trimeric structures that assemble into hexameric and higher-order molecular forms. Circulating levels of CTRP1 (C1qTNF1) are elevated in obesity, hypertension, and diabetes but can be decreased in the serum of diet-induced obese mice.

Products:

• Primary Antibodies
• cDNA Clones
• Proteins & Enzymes