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CA125/MUC16 Antibody (X52)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-11624

Novus Biologicals, part of Bio-Techne
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NBP2-11624-0.2mg

Key Product Details

Species Reactivity

Human

Applications

Sandwich ELISA, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # X52

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Hybridoma clone has been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with CA125 antigen purified from human ovarian carcinoma (MW > 1 MDa).

Epitope

B2 Epitope group

Specificity

CA125 antigen. Epitope specificity group B (ISOBM class Immunofluorescenceication) similar to M-11

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for CA125/MUC16 Antibody (X52)

Application
Recommended Usage

Sandwich ELISA

1:100-1:2000
Application Notes
Detection of CA125 antigen. Suggested pairs for sandwich immunoassay (capture-detection): NB120-10032 - NBP2-11624.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

PBS (pH 7.4)

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C. Do not freeze.

Background: CA125/MUC16

MUC16 (CA125) is a serum marker that is used routinely in gynecologic practice to monitor patients with ovarian cancer. It is a mullerian duct differentiation antigen that is over expressed in epithelial ovarian cancer cells and secreted into the blood, although its expression is not entirely confined to ovarian cancer. Most biochemical studies have concluded that MUC16 is a high molecular mass glycoprotein, although estimates of its size range from 200 to 2000 kDa with smaller "subunits" being described by some investigators.

Long Name

Ovarian Cancer Antigen CA125

Alternate Names

MUC16

Gene Symbol

MUC16

UniProt

Additional CA125/MUC16 Products

Product Documents for CA125/MUC16 Antibody (X52)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CA125/MUC16 Antibody (X52)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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