Cadherin-11 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-52046

Novus Biologicals, part of Bio-Techne
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NBP1-52046
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Cadherin-11 Antibodies »

Product Specifications

Immunogen

Peptide with sequence CESDQTKPLSNQP corresponding to internal region according to NP_001788.2.

Epitope

CESDQTKPLSNQP

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Cadherin-11 Antibody

Western Blot: Cadherin-11 Antibody [NBP1-52046]

Western Blot: Cadherin-11 Antibody [NBP1-52046]

Western Blot: Cadherin-11 Antibody [NBP1-52046] - HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human CDH11 with C-terminal MYC tag probed with this antibody (1ug/ml) in Lane A and probed with anti-MYC Tag (1/1000) in lane C. Mock-transfected HEK293 probed with (1mg/ml) in Lane B.

Applications for Cadherin-11 Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:8000

Western Blot

0.1 - 0.5 ug/ml
Application Notes
WB: In transfected HEK293 transiently expressing full-length human CDH11 (myc and DYKDDDDK tagged), a band of approx. 130 kDa band was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-myc tag antibody.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cadherin-11

This gene encodes a type II classical cadherin from the cadherin superfamily, integral membrane proteins that mediate calcium-dependent cell-cell adhesion. Mature cadherin proteins are composed of a large N-terminal extracellular domain, a single membrane-spanning domain, and a small, highly conserved C-terminal cytoplasmic domain. Type II (atypical) cadherins are defined based on their lack of a HAV cell adhesion recognition sequence specific to type I cadherins. Expression of this particular cadherin in osteoblastic cell lines, and its upregulation during differentiation, suggests a specific function in bone development and maintenance.

Alternate Names

Cadherin11, CDH11, CDHOB, OB-Cadherin

Entrez Gene IDs

1009 (Human); 84407 (Rat)

Gene Symbol

CDH11

UniProt

NP_001788.2 (Human)

Additional Cadherin-11 Products

Product Documents for Cadherin-11 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Cadherin-11 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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