Cadherin-6/KCAD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-87588

Novus Biologicals, part of Bio-Techne
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NBP1-87588
NBP1-87588-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Predicted:

Mouse (98%), Rat (100%). Backed by our 100% Guarantee.

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cadherin-6/KCAD Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: LDRETLLWHNITVIATEINNPKQSSRVPLYIKVLDVNDNAPEFAEFYETFVCEKAKADQLIQTLHAVDKDDPYSGHQFSFSLAPEAASGSNFTIQDNKDNTAGILTRKNGYNRHEMSTYLLP

Reactivity Notes

Reactivity reported in scientific literature (PMID: 24069422)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cadherin-6/KCAD Antibody

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588] - Staining of human lymph node shows low expression as expected.
Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588] - Staining of human kidney shows high expression.
Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588]

Immunohistochemistry-Paraffin: Cadherin-6/KCAD Antibody [NBP1-87588] - Staining in human kidney and lymph node tissues using anti-CDH6 antibody. Corresponding CDH6 RNA-seq data are presented for the same tissues.

Applications for Cadherin-6/KCAD Antibody

Application
Recommended Usage

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
HIER pH6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cadherin-6/KCAD

K Cadherin encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion.

Alternate Names

Cadherin6, CDH6, K-Cadherin

Gene Symbol

CDH6

Additional Cadherin-6/KCAD Products

Product Documents for Cadherin-6/KCAD Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cadherin-6/KCAD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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