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Cadherin-6/KCAD Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-17011

Novus Biologicals, part of Bio-Techne
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NBP2-17011

Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (98%), Mouse (97%), Rat (98%). Backed by our 100% Guarantee.

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for Cadherin-6/KCAD Antibody

Immunogen

Recombinant protein encompassing a sequence within the center region of human Cadherin-6/KCAD. The exact sequence is proprietary.

Reactivity Notes

Chicken (85%).

Localization

Cell membrane

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

88 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Cadherin-6/KCAD Antibody

Western Blot: Cadherin-6/KCAD Antibody [NBP2-17011]

Western Blot: Cadherin-6/KCAD Antibody [NBP2-17011]

Western Blot: Cadherin-6/KCAD Antibody [NBP2-17011] - Sample (30 ug of whole cell lysate) A: H1299 B: HCT116 7. 5% SDS PAGE gel, diluted at 1:2000.

Applications for Cadherin-6/KCAD Antibody

Application
Recommended Usage

Western Blot

1:500-1:3000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Reviewed Applications

Read 1 review rated 4 using NBP2-17011 in the following applications:

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Formulation

PBS (pH 7), 20% Glycerol

Preservative

0.01% Thimerosal

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cadherin-6/KCAD

This gene encodes a type II classical cadherin from the cadherin superfamily. The encoded membrane protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Cadherins mediate cell-cell binding in a homophilic manner, contributing to the sorting of heterogeneous cell types and the maintenance of orderly structures such as epithelium. Strong transcriptional expression of this gene has been observed in hepatocellular and renal carcinoma cell lines, suggesting a possible role in metastasis and invasion. [provided by RefSeq]

Alternate Names

Cadherin6, CDH6, K-Cadherin

Gene Symbol

CDH6

UniProt

Additional Cadherin-6/KCAD Products

Product Documents for Cadherin-6/KCAD Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Cadherin-6/KCAD Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.