Calcium-sensing R/CaSR Antibody - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-41271

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Cited:

Mouse

Predicted:

Bovine (100%). Backed by our 100% Guarantee.

Applications

Validated:

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry Free-Floating, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all Calcium-sensing R/CaSR Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 15 amino acid peptide near the amino terminus of human CASR. The immunogen is located within the first 50 amino acids of CASR. Amino Acid Squence: TSAYGPDQRAQKKGD

Specificity

At least two isoforms of CASR are known to exist.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

115, 125 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Calcium-sensing R/CaSR Antibody - BSA Free

Western Blot: Calcium-sensing R/CaSR AntibodyBSA Free [NBP2-41271]

Western Blot: Calcium-sensing R/CaSR AntibodyBSA Free [NBP2-41271]

Western Blot: Calcium-sensing R/CaSR Antibody [NBP2-41271] - Western blot analysis of CASR in EL4 cell lysate with CASR antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.
Immunocytochemistry/ Immunofluorescence: Calcium-sensing R/CaSR Antibody - BSA Free [NBP2-41271]

Immunocytochemistry/ Immunofluorescence: Calcium-sensing R/CaSR Antibody - BSA Free [NBP2-41271]

Immunocytochemistry/Immunofluorescence: Calcium-sensing R/CaSR Antibody [NBP2-41271] - Immunofluorescence of Calcium-sensing R/CASR in human kidney tissue with Calcium-sensing R/CASR antibody at 20 ug/mL.
Immunohistochemistry: Calcium-sensing R/CaSR Antibody - BSA Free [NBP2-41271]

Immunohistochemistry: Calcium-sensing R/CaSR Antibody - BSA Free [NBP2-41271]

Immunohistochemistry: Calcium-sensing R/CaSR Antibody [NBP2-41271] - Immunohistochemistry of Calcium-sensing R/CASR in human kidney tissue with Calcium-sensing R/CASRantibody at 5 ug/mL.

Applications for Calcium-sensing R/CaSR Antibody - BSA Free

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

20 ug/mL

Immunohistochemistry

5 ug/mL

Immunohistochemistry-Paraffin

5 ug/mL

Western Blot

1 - 2 ug/ml
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Calcium-sensing R/CaSR

Calcium-Sensing Receptor (CaSR) is a member of the G protein-coupled receptor family. CaSR is an integral membrane protein that senses changes in the extracellular concentration of calcium ions and controls the release of parathyroid hormone. The activity of the calcium-sensing receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system.

Mutations that inactivate CaSR lead to familial hypocalciuric hypercalcemia, whereas mutations that activate CaSR cause autosomal dominant hypocalcemia. Calcium-Sensing Receptor antibodies are useful tools for parathyroid studies and research on cellular calcium homeostasis regulation.

Long Name

Calcium-sensing Receptor

Alternate Names

CAR, CaSR, EIG8, FHH, FIH, GPRC2A, HHC1, NSHPT, PCaR1

Gene Symbol

CASR

Additional Calcium-sensing R/CaSR Products

Product Documents for Calcium-sensing R/CaSR Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Calcium-sensing R/CaSR Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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