Caldesmon/CALD1 Antibody (rCALD1/820) [HRP]
Novus Biologicals, part of Bio-Techne | Catalog # NBP3-08326H
Recombinant Monoclonal Antibody
Conjugate
Catalog #
Forumulation
Catalog #
Key Product Details
Species Reactivity
Validated:
Human
Applications
Immunohistochemistry-Paraffin, Western Blot
Label
HRP
Antibody Source
Monoclonal Mouse IgG1 kappa Clone # rCALD1/820
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Product Summary for Caldesmon/CALD1 Antibody (rCALD1/820) [HRP]
Immunogen
Recombinant full-length human Caldesmon/CALD1 protein (Uniprot: Q05682 )
Reactivity Notes
Does not react with rat. Others not known.
Localization
Cytoplasmic
Specificity
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120 150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70 80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. This monoclonal antibody recognizes only the 150kDa variant (h-caldesmon) in Western blots of human aortic media extracts and is unreactive with fibroblast extracts from cultivated human foreskin. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Marker
Smooth Muscle Marker
Clonality
Monoclonal
Host
Mouse
Isotype
IgG1 kappa
Applications for Caldesmon/CALD1 Antibody (rCALD1/820) [HRP]
Application
Recommended Usage
Immunohistochemistry-Paraffin
Optimal dilutions of this antibody should be experimentally determined.
Western Blot
Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.
Formulation, Preparation, and Storage
Purification
Protein A or G purified
Formulation
PBS
Preservative
No Preservative
Concentration
Please see the vial label for concentration. If unlisted please contact technical services.
Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store at 4C in the dark.
Background: Caldesmon/CALD1
Alternate Names
CALD1, CDM, HCAD, LCAD, NAG22
Gene Symbol
CALD1
Additional Caldesmon/CALD1 Products
Product Documents for Caldesmon/CALD1 Antibody (rCALD1/820) [HRP]
Product Specific Notices for Caldesmon/CALD1 Antibody (rCALD1/820) [HRP]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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