CaMKK2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86651

Novus Biologicals, part of Bio-Techne
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NBP1-86651
NBP1-86651-25ul
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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Cited:

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CaMKK2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: SSCVSSQPSSNRAAPQDELGGRGSSSSESQKPCEALRGLSSLSIHLGMESFIVVTECEPGCAVDLGLARDRPLEADGQEVPLDTSGSQARPHLSGRKLSLQERSQGGLAAGGSLDMNGRCICPSLPYSPVSSPQSS

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Rat (81%)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CaMKK2 Antibody

Western Blot: CaMKK2 Antibody [NBP1-86651]

Western Blot: CaMKK2 Antibody [NBP1-86651]

Western Blot: CaMKK2 Antibody [NBP1-86651] - Analysis in human cerebral cortex tissue.
Immunocytochemistry/ Immunofluorescence: CaMKK2 Antibody [NBP1-86651]

Immunocytochemistry/ Immunofluorescence: CaMKK2 Antibody [NBP1-86651]

Immunocytochemistry/Immunofluorescence: CaMKK2 Antibody [NBP1-86651] - Staining of human cell line A-431 shows localization to cytosol. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: CaMKK2 Antibody [NBP1-86651]

Immunohistochemistry-Paraffin: CaMKK2 Antibody [NBP1-86651]

Immunohistochemistry-Paraffin: CaMKK2 Antibody [NBP1-86651] - Staining of human cerebral cortex shows moderate cytoplasmic positivity in neurons.
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Applications for CaMKK2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000

Western Blot

0.04-0.4 ug/ml
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CaMKK2

The product of this gene belongs to the Serine/Threonine protein kinase family, and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. This protein plays a role in the calcium/calmodulin-dependent (CaM) kinase cascade by phosphorylating the downstream kinases CaMK1 and CaMK4. Seven transcript variants encoding six distinct isoforms have been identified for this gene. Additional splice variants have been described but their full-length nature has not been determined. The identified isoforms exhibit a distinct ability to undergo autophosphorylation and to phosphorylate the downstream kinases. [provided by RefSeq]

Long Name

Calcium/calmodulin-dependent protein kinase kinase 2

Alternate Names

CaM-kinase kinase 2, CaM-KK 2, CaM-KK beta, CaMKK 2, CaMKK beta, CAMKKB, KIAA0787

Gene Symbol

CAMKK2

Additional CaMKK2 Products

Product Documents for CaMKK2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CaMKK2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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