Carbonic Anhydrase IV/CA4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-88226

Novus Biologicals, part of Bio-Techne
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NBP1-88226
NBP1-88226-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Carbonic Anhydrase IV/CA4 Antibodies »

Product Summary for Carbonic Anhydrase IV/CA4 Antibody

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: VTTKAKVDKKLGRFFFSGYDKKQTWTVQNNGHSVMMLLENKASISGGGLPAPYQAKQLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNVKEAQDPEDEIAVLA

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Carbonic Anhydrase IV/CA4 Antibody

Carbonic Anhydrase IV/CA4 Antibody

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226] -

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226] - Analysis in human rectum and lymph node tissues using NBP1-88226 antibody. Corresponding CA4 RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226]

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226]

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226] - Staining of human rectum shows strong membranous positivity in glandular cells.
Carbonic Anhydrase IV/CA4 Antibody

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226] -

Immunohistochemistry-Paraffin: Carbonic Anhydrase IV/CA4 Antibody [NBP1-88226] - Staining of human lymph node shows no positivity in non-germinal center cells as expected.

Applications for Carbonic Anhydrase IV/CA4 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carbonic Anhydrase IV/CA4

Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. This gene encodes a glycosylphosphatidyl-inositol-anchored membrane isozyme expressed on the luminal surfaces of pulmonary (and certain other) capillaries and proximal renal tubules. Its exact function is not known; however, it may have a role in inherited renal abnormalities of bicarbonate transport. [provided by RefSeq]

Alternate Names

CA4, RP17

Gene Symbol

CA4

Additional Carbonic Anhydrase IV/CA4 Products

Product Documents for Carbonic Anhydrase IV/CA4 Antibody

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Carbonic Anhydrase IV/CA4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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