Carboxylesterase 2/CES2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-25334

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Carboxylesterase 2/CES2 Antibodies »

Product Specifications

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein xxxCES2xxx using the following amino acid sequence: ESGVALLPGLIASSADVISTVVANLSACDQVDSEALVGCLRGKSKEEILAINKPFKMIPGVVDGVFLPRHPQELLASADF

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Carboxylesterase 2/CES2 Antibody

Carboxylesterase 2/CES2 Antibody Immunohistochemistry-Paraffin: Carboxylesterase 2/CES2 Antibody [NBP3-25334]

Immunohistochemistry-Paraffin: Carboxylesterase 2/CES2 Antibody [NBP3-25334]

Staining of human small intestine shows strong cytoplasmic positivity in glandular cells.
Carboxylesterase 2/CES2 Antibody Western Blot: Carboxylesterase 2/CES2 Antibody [NBP3-25334]

Western Blot: Carboxylesterase 2/CES2 Antibody [NBP3-25334]

Analysis in human cell line RT-4, human cell line U-251 MG, human plasma and human liver tissue.

Applications for Carboxylesterase 2/CES2 Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500

Western Blot

0.04-0.4 µg/ml
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Carboxylesterase 2/CES2

Carboxylesterase 2 is a member of a large multigene family. The enzymes encoded by these genes are responsible for the hydrolysis of ester- and amide-bond-containing drugs such as cocaine and heroin. They also hydrolize long-chain fatty acid esters and thioesters. The specific function of this enzyme has not yet been determined; however, it is speculated that carboxylesterases may play a role in lipid metabolism and/or the blood-brain barrier system. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

Alternate Names

CE-2, CES2, PCE-2

Gene Symbol

CES2

Additional Carboxylesterase 2/CES2 Products

Product Documents for Carboxylesterase 2/CES2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Carboxylesterase 2/CES2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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