Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # OTI3D5

Concentration

1 mg/ml

View all Carboxypeptidase B2/CPB2 Antibodies »

Product Specifications

Immunogen

Human recombinant protein fragment corresponding to amino acids 224-423 of human CPB2(NP_001863) produced in E.coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

45.9 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Carboxypeptidase B2/CPB2 Antibody (OTI3D5)

Immunohistochemistry: Carboxypeptidase B2/CPB2 Antibody (OTI3D5) [NBP2-46345]

Immunohistochemistry: Carboxypeptidase B2/CPB2 Antibody (OTI3D5) [NBP2-46345]

Immunohistochemistry: Carboxypeptidase B2/CPB2 Antibody (3D5) [NBP2-46345] - Analysis of Carcinoma of Human lung tissue. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120C for 3min)

Applications for Carboxypeptidase B2/CPB2 Antibody (OTI3D5)

Application
Recommended Usage

Immunohistochemistry

1:150

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.3), 1.0% BSA and 50% Glycerol

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Carboxypeptidase B2/CPB2

Carboxypeptidases are enzymes that hydrolyze C-terminal peptide bonds. The carboxypeptidase family includes metallo-, serine, and cysteine carboxypeptidases. According to their substrate specificity, these enzymes are referred to as carboxypeptidase A (cleaving aliphatic residues) or carboxypeptidase B (cleaving basic amino residues). The protein encoded by this gene is activated by trypsin and acts on carboxypeptidase B substrates. After thrombin activation, the mature protein downregulates fibrinolysis. Polymorphisms have been described for this gene and its promoter region. Available sequence data analyses indicate splice variants that encode different isoforms. [provided by RefSeq]

Alternate Names

CPB2, CPU, TAFI

Gene Symbol

CPB2

Additional Carboxypeptidase B2/CPB2 Products

Product Documents for Carboxypeptidase B2/CPB2 Antibody (OTI3D5)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Carboxypeptidase B2/CPB2 Antibody (OTI3D5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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