Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Mouse (92%). Backed by our 100% Guarantee.

Applications

ELISA, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CARD14 Antibodies »

Product Specifications

Immunogen

CARMA2 antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human CARMA2. The immunogen is located within the last 50 amino acids of CARMA2. Amino Acid Squence: DEQKKVVWTEQSPR

Specificity

CARD14 antibody is human specific. At least three isoforms of CARD14 are known to exist; this antibody will only detect isoform 1. CARD14 antibody is predicted not to cross-react with other CARMA proteins.

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CARD14 Antibody - BSA Free

CARD14 Antibody - BSA Free

Immunohistochemistry: CARD14 Antibody - BSA Free [NBP2-81901] -

Immunohistochemistry: CARD14 Antibody - BSA Free [NBP2-81901] - Immunohistochemistry of CARD14 in human placenta tissue with CARD14 antibody at 5 ug/mL.

Applications for CARD14 Antibody - BSA Free

Application
Recommended Usage

Immunohistochemistry

5 ug/ml

Immunohistochemistry-Paraffin

5 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CARD14

The protein encoded by the CARD14 gene belongs to the membrane-associated guanylate kinase (MAGUK) family, a class ofproteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions ofthe plasma membrane. This protein is also a member of the CARD protein family, which is defined by carrying acharacteristic caspase-associated recruitment domain (CARD). This protein shares a similar domain structure withCARD11 protein. The CARD domains of both proteins have been shown to specifically interact with BCL10, a protein knownto function as a positive regulator of cell apoptosis and NF-kappaB activation. When expressed in cells, this proteinactivated NF-kappaB and induced the phosphorylation of BCL10. Two alternatively spliced variants of this gene encodingdistinct isoforms have been reported. (provided by RefSeq)

Alternate Names

bcl10-interacting maguk protein 2, BIMP2, CARD-containing MAGUK protein 2, card-maguk protein 2, Carma 2, CARMA2CARD-containing MAGUK 2 protein, caspase recruitment domain family, member 14, caspase recruitment domain-containing protein 14

Gene Symbol

CARD14

Additional CARD14 Products

Product Documents for CARD14 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CARD14 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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