Caspase-2 Antibody (10C6) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-80095

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat, Canine, Monkey

Applications

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry

Label

Unconjugated

Antibody Source

Monoclonal Rat IgG2a Kappa Clone # 10C6

Format

BSA Free

Concentration

1 mg/ml

View all Caspase-2 Antibodies »

Product Summary for Caspase-2 Antibody (10C6) - BSA Free

Immunogen

Recombinant human caspase-2 (p19 subunit).

Specificity

Recognizes an epitope in the p19 subunit of human, mouse, rat, monkey and dog caspase-2.

Clonality

Monoclonal

Host

Rat

Isotype

IgG2a Kappa

Scientific Data Images for Caspase-2 Antibody (10C6) - BSA Free

Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]

Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]

Immunocytochemistry/Immunofluorescence: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095] - HeLa cells were fixed, permeabilised, stained using Caspase-2, mAb (10C6) (Prod. No. NBP2-80095)
Flow Cytometry: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]

Flow Cytometry: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095]

Flow Cytometry: Caspase-2 Antibody (10C6) - BSA Free [NBP2-80095] - Data of 293T cells transiently transfected with HA-tagged caspase-2, fixed with 1% PFA, permeabilized with saponin and stained intracellularly with using Caspase-2, mAb (10C6) (Prod. No.NBP2-80095)

Applications for Caspase-2 Antibody (10C6) - BSA Free

Application
Recommended Usage

ELISA

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Caspase-2

Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the initiation and execution of apoptosis. They are expressed as latent zymogens and are activated by an autoproteolytic mechanism or by processing by other proteases (frequently other caspases). Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7).

Caspases are regulated by a variety of stimili, including APAF1, CFLAR/FLIP, NOL3/ARC, and members of the inhibitor of apoptosis (IAP) family such as BIRC1/NAIP, BIRC2/cIAP-1, BIRC3/cIAP-2, BIRC4/XIAP, BIRC5/Survivin, and BIRC7/Livin. IAP activity is modulated by DIABLO/SMAC or PRSS25/HTRA2/Omi. Cell-permeable and irreversible peptide inhibitors are also available for different caspases.

Alternate Names

CASP2, Caspase2, ICH-1, NEDD2

Gene Symbol

CASP2

Additional Caspase-2 Products

Product Documents for Caspase-2 Antibody (10C6) - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Caspase-2 Antibody (10C6) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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