Caspase-2 Antibody (1C11) - (active/cleaved)

Novus Biologicals, part of Bio-Techne | Catalog # H00000835-M10

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 1C11

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Caspase-2 Antibodies »

Product Specifications

Immunogen

CASP2 (AAH02427, 121 a.a. ~ 220 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. TLSGLQHVLPPLSCDYDLSLPFPVCESCPLYKKLRLSTDTVEHSLDNKDGPLCLQVKPCTPEFYQTHFQLAYRLQSRPRGLALVLSNVHFTGEKELEFRS

Specificity

CASP2 - caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Caspase-2 Antibody (1C11) - (active/cleaved)

Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (1C11) - (active/cleaved) [H00000835-M10]

Immunocytochemistry/ Immunofluorescence: Caspase-2 Antibody (1C11) - (active/cleaved) [H00000835-M10]

Immunocytochemistry/Immunofluorescence: Caspase-2 Antibody (1C11) - (active/cleaved) [H00000835-M10] - Analysis of monoclonal antibody to CASP2 on HeLa cell. Antibody concentration 10 ug/ml

Applications for Caspase-2 Antibody (1C11) - (active/cleaved)

Application
Recommended Usage

Western Blot

1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Caspase-2

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The proteolytic cleavage of this protein is induced by a variety of apoptotic stimuli. Alternative splicing of this gene results in multiple transcript variants that encode different isoforms.

Alternate Names

CASP2, Caspase2, ICH-1, NEDD2

Gene Symbol

CASP2

OMIM

600639 (Human)

Additional Caspase-2 Products

Product Documents for Caspase-2 Antibody (1C11) - (active/cleaved)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Caspase-2 Antibody (1C11) - (active/cleaved)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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