Key Product Details

Species Reactivity

Human, Mouse, Rat, Porcine, Canine, Hamster, Primate, Rabbit, Sheep

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 7-1-11

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Caspase-7 Antibodies »

Product Specifications

Immunogen

Recombinant human Caspase-7 protein (full length)

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Specificity

Caspase-7 (7-1-11)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Scientific Data Images for Caspase-7 Antibody (7-1-11)

Western Blot: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Western Blot: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Western Blot: Caspase-7 Antibody (7-1-11) [NBP1-19229] - Analysis of Caspase-7, mAb (7-1-11): Lane1: MW Marker; Lane 2: Jurkat ; Lane 3: Jurkat plus Staurosporine; Lane 4: HeLa ; Lane 5: HeLa plus Nocodazole; Lane 6: 3T3 ; Lane 7: PC-12
Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229] - Human spleen tissue stained with Caspase-7, mAb (7-1-11) at 10ug/ml.
Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229]

Immunohistochemistry: Caspase-7 Antibody (7-1-11) [NBP1-19229] - Human colon tissue stained with Caspase-7, mAb (7-1-11) at 10ug/ml.
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Applications for Caspase-7 Antibody (7-1-11)

Application
Recommended Usage

Western Blot

1:100-1:2000

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS, pH 7.2, 0.1mM PMSF.

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caspase-7

Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates. Caspases have the ability to cleave after aspartic acid residues. There are two classes of caspases involved in apoptosis; initiators (activation by receptor cluster) and effectors (activation by mitochondrial permeability transition). Proapoptotic signals autocatalytically activate initiator caspases, such as Caspase 8 and Caspase 9. Activated initiator caspases then process effector caspases, such as Caspase 3 and Caspase 7, which in turn cause cell collapse.

Alternate Names

CASP7, Caspase7, Mch3

Entrez Gene IDs

840 (Human); 12369 (Mouse); 64026 (Rat)

Gene Symbol

CASP7

Additional Caspase-7 Products

Product Documents for Caspase-7 Antibody (7-1-11)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Caspase-7 Antibody (7-1-11)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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