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Caspase-7 Antibody (MCH3-5)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-30814

Novus Biologicals, part of Bio-Techne
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NBP3-30814-100ug
NBP3-30814-25ug

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG Clone # MCH3-5

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant human Caspase-7 protein and mouse myeloma cells.

Specificity

Detects proenzyme form of human Caspase-7 by Western blot.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG

Scientific Data Images for Caspase-7 Antibody (MCH3-5)

Caspase-7 Antibody (MCH3-5)

Western Blot: Caspase-7 Antibody (MCH3-5) [NBP3-30814] -

Western Blot: Caspase-7 Antibody (MCH3-5) [NBP3-30814] - Western blot analysis using caspase-7antibody on MCF-7 cells treated with thapsigarginfor 48 hours which are negative (-) and positive(+) for caspase-3.

Applications for Caspase-7 Antibody (MCH3-5)

Application
Recommended Usage

Western Blot

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
.

Formulation, Preparation, and Storage

Purification

Ammonium sulfate precipitation

Formulation

Phosphate buffered saline

Preservative

0.08% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Caspase-7

Caspase 7 (CASP7) is a member of the cysteine-aspartic acid protease (caspase) family that is involved in the execution-phase of cell apoptosis. The sequential activation of caspases plays a central role in the execution-phase of cell apoptosis, and Caspase 7 is an executioner protein of apoptosis. It is activated upon cell death stimuli and induces apoptosis.

Caspase 7 is expressed as an inactive proenzyme which then undergos proteolytic processing by upstream caspases, to form an active (cleaved) caspase 7 form.

Caspase 7 antibodies are important tools for apoptosis studies and research on the caspase family mediated apoptosis signaling pathway.

Alternate Names

CASP7, Caspase7, Mch3

Gene Symbol

CASP7

Additional Caspase-7 Products

Product Documents for Caspase-7 Antibody (MCH3-5)

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for Caspase-7 Antibody (MCH3-5)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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