Caspr2 Antibody (SR1224)

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-22366

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne
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NBP3-22366-100ul
NBP3-22366-50ul
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Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Immunohistochemistry, Western Blot

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # SR1224

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Caspr2 Antibodies »

Product Summary for Caspr2 Antibody (SR1224)

Immunogen

A synthesized peptide derived from human Caspr2 (Uniprot #: Q9UHC6)

Specificity

Detects endogenous levels of total Caspr2

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Theoretical MW

160 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for Caspr2 Antibody (SR1224)

Western Blot: Caspr2 Antibody (SR1224) [NBP3-22366] -

Western Blot: Caspr2 Antibody (SR1224) [NBP3-22366] - Western blot analysis using NBP3-22366 in Mouse brain lysate.

Applications for Caspr2 Antibody (SR1224)

Application
Recommended Usage

Immunohistochemistry

1:100-1:500

Western Blot

1:500-1:1000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.4, 150mM NaCl, 50% glycerol.

Preservative

0.02% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Caspr2

Caspr2 encodes a member of the neurexin family which functions in the vertebrate nervous system as cell adhesion molecules and receptors. This protein, like other neurexin proteins, contains epidermal growth factor repeats and laminin G domains. In addition, it includes an F5/8 type C domain, discoidin/neuropilin- and fibrinogen-like domains, thrombospondin N-terminal-like domains and a putative PDZ binding site. This protein is localized at the juxtaparanodes of myelinated axons and associated with potassium channels. It may play a role in the local differentiation of the axon into distinct functional subdomains. This gene encompasses almost 1.5% of chromosome 7 and is one of the largest genes in the human genome. It may represent a positional candidate gene for the DFNB13 form of nonsyndromic deafness.

Long Name

Contactin Associated Protein-like 2

Alternate Names

CDFE, CNTNAP2, NRXN4

Gene Symbol

CNTNAP2

Additional Caspr2 Products

Product Documents for Caspr2 Antibody (SR1224)

Product Datasheets

Certificate of Analysis

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Product Specific Notices for Caspr2 Antibody (SR1224)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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