Cathepsin B Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-86048

Novus Biologicals, part of Bio-Techne
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NBP1-86048
NBP1-86048-25ul
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cathepsin B Antibodies »

Product Specifications

Immunogen

This antibody was developed against Recombinant Protein corresponding to amino acids: DELVNYVNKRNTTWQAGHNFYNVDMSYLKRLCGTFLGGPKPPQRVMFTEDLKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAEDLLTCCGSMCGDGCNGGYPA

Reactivity Notes

Reactivity reported in scientific literature (PMID: 22918166)

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cathepsin B Antibody

Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048]

Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048]

Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048] - Staining in human thyroid gland and skeletal muscle tissues . Corresponding CTSB RNA-seq data are presented for the same tissues.
Immunocytochemistry/ Immunofluorescence: Cathepsin B Antibody [NBP1-86048]

Immunocytochemistry/ Immunofluorescence: Cathepsin B Antibody [NBP1-86048]

Immunocytochemistry/Immunofluorescence: Cathepsin B Antibody [NBP1-86048] - Staining of human cell line A-431 shows localization to nucleoli & vesicles. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048]

Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048]

Immunohistochemistry-Paraffin: Cathepsin B Antibody [NBP1-86048] - Staining of human thyroid gland shows moderate granular cytoplasmic positivity in glandular cells.
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Applications for Cathepsin B Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:500 - 1:1000

Immunohistochemistry-Paraffin

1:500 - 1:1000
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: PFA/Triton X-100

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cathepsin B

The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S and O. The aspartyl protease class is composed of cathepsins D and E. cathepsin G is in the serine protease class. Most cathepsins are lysosomal and each is involved in cellular metabolism, participating in various events such as peptide biosynthesis and protein degradation. cathepsin B is expressed in luminal epithelial cells, indicating that cathepsin B is a marker for secretory cell death.

Alternate Names

CTSB

Gene Symbol

CTSB

Additional Cathepsin B Products

Product Documents for Cathepsin B Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cathepsin B Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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