Cathepsin K Antibody (2F1)

Novus Biologicals, part of Bio-Techne | Catalog # H00001513-M01

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2a Kappa Clone # 2F1

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cathepsin K Antibodies »

Product Specifications

Immunogen

CTSK (AAH16058, 220 a.a. ~ 329 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. KCRGYREIPEGNEKALKRAVARVGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKNSWGENWGNKGYILMARNKNNACGIANLASFPKM

Specificity

CTSK (2F1)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2a Kappa

Description

Quality control test: Antibody Reactive Against Recombinant Protein.

Scientific Data Images for Cathepsin K Antibody (2F1)

Western Blot: Cathepsin K Antibody (2F1) [H00001513-M01]

Western Blot: Cathepsin K Antibody (2F1) [H00001513-M01]

Western Blot: Cathepsin K Antibody (2F1) [H00001513-M01] - Analysis of CTSK expression in transfected 293T cell line by CTSK monoclonal antibody (M01), clone 2F1.Lane 1: CTSK transfected lysate(37 KDa).Lane 2: Non-transfected lysate.
Immunocytochemistry/ Immunofluorescence: Cathepsin K Antibody (2F1) [H00001513-M01]

Immunocytochemistry/ Immunofluorescence: Cathepsin K Antibody (2F1) [H00001513-M01]

Immunocytochemistry/Immunofluorescence: Cathepsin K Antibody (2F1) [H00001513-M01] - HeLa cell.
Immunohistochemistry-Paraffin: Cathepsin K Antibody (2F1) [H00001513-M01]

Immunohistochemistry-Paraffin: Cathepsin K Antibody (2F1) [H00001513-M01]

Immunohistochemistry-Paraffin: Cathepsin K Antibody (2F1) [H00001513-M01] - Analysis of monoclonal antibody to CTSK on formalin-fixed paraffin-embedded human kidney. Antibody concentration 3 ug/ml.
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Applications for Cathepsin K Antibody (2F1)

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

10 ug/ml

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Paraffin

1:10-1:500

Western Blot

1:500
Application Notes
Antibody reactivity against transfected lysate and recombinant protein for WB. It has been used for IHC-P and ELISA.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

IgG purified

Formulation

In 1x PBS, pH 7.4

Preservative

No Preservative

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.

Background: Cathepsin K

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.

Alternate Names

CTS02, CTSK, CTSO1, CTSO2, PKND, PYCD

Entrez Gene IDs

1513 (Human)

Gene Symbol

CTSK

OMIM

265800 (Human)

UniProt

AAH16058 (Human)

Additional Cathepsin K Products

Product Documents for Cathepsin K Antibody (2F1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cathepsin K Antibody (2F1)

This product is produced by and distributed for Abnova, a company based in Taiwan.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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