Cathepsin K Antibody (CTSK/2793) [Janelia Fluor® 525]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-79900JF525

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin, Protein Array

Label

Janelia Fluor 525

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # CTSK/2793

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all Cathepsin K Antibodies »

Product Summary for Cathepsin K Antibody (CTSK/2793) [Janelia Fluor® 525]

Immunogen

Recombinant fragment of human Cathepsin K protein (around aa 163-274) (exact sequence is proprietary) (Uniprot: P43235)

Localization

Cytoplasmic

Marker

Marker of Tumor Invasiveness

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for Cathepsin K Antibody (CTSK/2793) [Janelia Fluor® 525]

Application
Recommended Usage

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Protein Array

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: Cathepsin K

Cathepsin K is encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Alternate Names

CTS02, CTSK, CTSO1, CTSO2, PKND, PYCD

Gene Symbol

CTSK

Additional Cathepsin K Products

Product Documents for Cathepsin K Antibody (CTSK/2793) [Janelia Fluor® 525]

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for Cathepsin K Antibody (CTSK/2793) [Janelia Fluor® 525]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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