Cathepsin K Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-94902

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Validated:

Human

Predicted:

Bovine (100%), Canine (100%), Mouse (100%), Porcine (100%), Rat (100%). Backed by our 100% Guarantee.

Applications

Peptide ELISA, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

0.5 mg/ml

View all Cathepsin K Antibodies »

Product Specifications

Immunogen

Peptide with sequence C-KTHRKQYNNKVDE corresponding to internal region (near N-Terminus) according to NP_000387.1.

Epitope

C-KTHRKQYNNKVDE

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for Cathepsin K Antibody

Western Blot: Cathepsin K Antibody [NB100-94902]

Western Blot: Cathepsin K Antibody [NB100-94902]

Western Blot: Cathepsin K Antibody [NB100-94902] - Staining of Human Lung lysate (35 ug protein in RIPA buffer). Antibody at 1 ug/mL. Primary incubation was 1 hour. Detected by chemiluminescence.

Applications for Cathepsin K Antibody

Application
Recommended Usage

Peptide ELISA

Detection limit 1:16000

Western Blot

1 - 3 ug/mL
Application Notes
WB: Approx. 36 kDa band observed in human lung and human ovary lysates (calculated MW of 37.0 kDa band according to NP_000387.1).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA

Preservative

0.02% Sodium Azide

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: Cathepsin K

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing. [provided by RefSeq]

Alternate Names

CTS02, CTSK, CTSO1, CTSO2, PKND, PYCD

Entrez Gene IDs

1513 (Human)

Gene Symbol

CTSK

UniProt

NP_000387.1 (Human)

Additional Cathepsin K Products

Product Documents for Cathepsin K Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cathepsin K Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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