Caveolin-3 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP3-24705

Novus Biologicals, part of Bio-Techne
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NBP3-24705
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Caveolin-3 Antibodies »

Product Summary for Caveolin-3 Antibody

Immunogen

This antibody has been engineered to specifically recognize the recombinant protein Caveolin-3 using the following amino acid sequence: MMAEEHTDLEAQIVKDIHCKEIDLV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Caveolin-3 Antibody

Caveolin-3 Antibody Immunohistochemistry-Paraffin: Caveolin-3 Antibody [NBP3-24705]

Immunohistochemistry-Paraffin: Caveolin-3 Antibody [NBP3-24705]

Staining of human skeletal muscle shows strong membranous positivity in myocytes.

Applications for Caveolin-3 Antibody

Application
Recommended Usage

Immunohistochemistry

1:200 - 1:500

Immunohistochemistry-Paraffin

1:200 - 1:500
Application Notes
For IHC-Paraffin, we recommend using Heat-Induced Epitope Retrieval (HIER) with a pH level of 6. This optimized retrieval method ensures the best results for your experiments.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS, pH 7.2, 40% glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Caveolin-3

Caveolin 3 encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.

Alternate Names

CAV3, Caveolin3, LGMD1C, LQT9, M-caveolin

Gene Symbol

CAV3

Additional Caveolin-3 Products

Product Documents for Caveolin-3 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Caveolin-3 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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