Cbx2 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-47524

Novus Biologicals, part of Bio-Techne
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NBP2-47524
NBP2-47524-25ul
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Key Product Details

Species Reactivity

Human

Applications

Validated:

Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin

Cited:

Immunohistochemistry

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all Cbx2 Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: KRDCVKGSATPSGQESRTAPGEARKAATLPEMSAGEESSSSDSDPDSASPPSTGQNPSVSVQTSQDWKPTRSLIEHVFVTDVTANLITVTVKESPTSV

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for Cbx2 Antibody

Immunocytochemistry/ Immunofluorescence: Cbx2 Antibody [NBP2-47524]

Immunocytochemistry/ Immunofluorescence: Cbx2 Antibody [NBP2-47524]

Immunocytochemistry/Immunofluorescence: Cbx2 Antibody [NBP2-47524] - Staining of human cell line A-431 shows localization to nucleoplasm. Antibody staining is shown in green.
Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524]

Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524]

Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524] - Staining of human liver shows no positivity in hepatocytes as expected.
Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524]

Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524]

Immunohistochemistry-Paraffin: Cbx2 Antibody [NBP2-47524] - Staining of human testis shows strong nuclear positivity in cells in seminiferous ducts.
View 2 more images

Applications for Cbx2 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Immunohistochemistry

1:50 - 1:200

Immunohistochemistry-Paraffin

1:50 - 1:200
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: Cbx2

Polycomb' genes in Drosophila maintain the repressed state of homeotic and other developmentally regulatedgenes (Wedeen et al., 1986 (PubMed 3081265); Kuziora and McGinnis, 1988 (PubMed 2903050)) by mediating changes inhigher-order chromatin structure (Paro and Hogness, 1991 (PubMed 1898775)). M33, a mouse homolog of polycomb, wasisolated by means of the structural similarity of its chromodomain (Pearce et al., 1992 (PubMed 1352241)). The fifthexon of M33 contains a region of homology shared by Drosophila and Xenopus. In Drosophila, its deletion results in theloss of polycomb function.(supplied by OMIM)

Long Name

Chromobox Homolog 2

Alternate Names

CDCA6, M33, SRXY5

Gene Symbol

CBX2

Additional Cbx2 Products

Product Documents for Cbx2 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for Cbx2 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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