Key Product Details

Species Reactivity

Human, Mouse, Rat

Applications

ELISA, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Format

BSA Free

Concentration

1 mg/ml

View all CCDC134 Antibodies »

Product Specifications

Immunogen

Antibody was raised against a 17 amino acid synthetic peptide near the amino terminus of human CCDC134. The immunogen is located within the first 50 amino acids of CCDC134. Amino Acid Squence: PLEIYKKMFEVKRREQ

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCDC134 Antibody - BSA Free

Western Blot: CCDC134 AntibodyBSA Free [NBP1-77053]

Western Blot: CCDC134 AntibodyBSA Free [NBP1-77053]

Western Blot: CCDC134 Antibody [NBP1-77053] - rat brain tissue lysate with CCDC134 antibody at (A) 1 and (B) 2 ug/ml.
Immunocytochemistry/ Immunofluorescence: CCDC134 Antibody - BSA Free [NBP1-77053]

Immunocytochemistry/ Immunofluorescence: CCDC134 Antibody - BSA Free [NBP1-77053]

Immunocytochemistry/Immunofluorescence: CCDC134 Antibody [NBP1-77053] - Immunofluorescence of CDCC134 in human brain tissue with CDCC134 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: CCDC134 Antibody - BSA Free [NBP1-77053]

Immunohistochemistry-Paraffin: CCDC134 Antibody - BSA Free [NBP1-77053]

Immunohistochemistry-Paraffin: CCDC134 Antibody [NBP1-77053] - Human brain tissue with CCDC134 antibody at 2.5 ug/ml.
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Applications for CCDC134 Antibody - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Immunocytochemistry/ Immunofluorescence

20 ug/ml

Immunohistochemistry

2.5 ug/ml

Immunohistochemistry-Paraffin

2.5 ug/ml

Western Blot

1-2 ug/ml

Formulation, Preparation, and Storage

Purification

Peptide affinity purified

Formulation

PBS

Format

BSA Free

Preservative

0.02% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCDC134

The coiled-coil domain is a common protein motif that is often involved in protein oligomerization and is found in proteins such as transcription factors and intermediate filaments. One such protein is CCDC134, a recently identified secretory protein that has been found to inhibit the transcriptional activity of the Elk1 protein. Overexpression CCDC134 also inhibited the phosphorylation of Erk and JNK/SAPK but not p38 MAPK, while specific siRNA against CCDC134 activated Elk1 transcriptional activity and the phosphorylation of Erk and JNK/SAPK, suggesting a potential inhibiting role of CCDC134 in MAPK-mediated Elk1 transcription. CCDC134 is widely expressing in normal adult tissues, tumors, and cell lines.

Long Name

Coiled-coil Domain Containing 134

Alternate Names

coiled-coil domain containing 134, coiled-coil domain-containing protein 134, dJ821D11.3, FLJ22349, MGC21013

Gene Symbol

CCDC134

UniProt

NP_079097 (Human)

Additional CCDC134 Products

Product Documents for CCDC134 Antibody - BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CCDC134 Antibody - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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