CCL2/MCP1 Antibody [DyLight 650]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-07035C

Submit a review

Product Datasheet / COA / SDS

View Available Conjugates View Available Formulations

Conjugate

Catalog #

Alexa Fluor 350

NBP1-07035AF350

Alexa Fluor 405

NBP1-07035AF405

Alexa Fluor 488

NBP1-07035AF488

Alexa Fluor 532

NBP1-07035AF532

Alexa Fluor 594

NBP1-07035AF594

Alexa Fluor 647

NBP1-07035AF647

Alexa Fluor 700

NBP1-07035AF700

Alexa Fluor 750

NBP1-07035AF750

Allophycocyanin

NBP1-07035APC

Biotin

NBP1-07035B

CoraFluor 1

NBP1-07035CL1

DyLight 350

NBP1-07035UV

DyLight 405

NBP1-07035V

DyLight 488

NBP1-07035G

DyLight 550

NBP1-07035R

DyLight 594

NBP1-07035DL594

DyLight 680

NBP1-07035FR

DyLight 755

NBP1-07035IR

FITC

NBP1-07035F

HRP

NBP1-07035H

Janelia Fluor 525

NBP1-07035JF525

Janelia Fluor 549

NBP1-07035JF549

Janelia Fluor 585

NBP1-07035JF585

Janelia Fluor 635

NBP1-07035JF635

Janelia Fluor 646

NBP1-07035JF646

Janelia Fluor 669

NBP1-07035JF669

mFluor Violet 450 SE

NBP1-07035MFV450

mFluor Violet 500 SE

NBP1-07035MFV500

mFluor Violet 610 SE

NBP1-07035MFV610

PE

NBP1-07035PE

PerCP

NBP1-07035PCP

Forumulation

Catalog #

BSA Free

NBP1-07035

Product Summary
Applications
Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species Reactivity

Validated:

Human, Mouse, Rat

Applications

Block/Neutralize, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Paraffin, Western Blot

Label

DyLight 650 (Excitation = 652 nm, Emission = 672 nm)

Antibody Source

Polyclonal Rabbit IgG

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CCL2/MCP1 Antibodies »

Product Summary for CCL2/MCP1 Antibody [DyLight 650]

Immunogen

Synthetic peptide made to an internal portion of rat MCP1 (within residues 15-40). [Swiss-Prot# P14844]

Localization

Secreted, secretory vesicles

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Applications for CCL2/MCP1 Antibody [DyLight 650]

Application

Recommended Usage

Block/Neutralize

Optimal dilutions of this antibody should be experimentally determined.

Immunocytochemistry/ Immunofluorescence

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Western Blot

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CCL2/MCP1

Rat MCP-1 (monocyte chemoattracctant protein-1) is a 148-amino acid CC chemokine with a NH2-terminal sequence of 29 residues as a signal sequence. This rat MCP-1/JE is 49-amino acid longer than human MCP-1 at 3-end. This 3-end is a serine and threonine rich zone, which is probably responsible for the extensive O-glycosylation. MCP-1 is produced by a wide range of cell types as a reaction to diverse inflammatory stimuli and is a chemotactic factor that attracts monocytes and basophils but not neutrophils or eosinophils. MCP-1 augments monocyte anti-tumor activity and has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis or atherosclerosis. In atherosclerosis MCP-1 may has been implicated to be involved in the recruitment of monocytes into the arterial wall during the disease process.

Alternate Names

C-C motif chemokine 2, chemokine (C-C motif) ligand 2, GDCF-2, HC11Monocyte secretory protein JE, MCAFMonocyte chemotactic and activating factor, MCP1 Monocyte chemotactic protein 1, MCP-1 Small-inducible cytokine A2, MGC9434, Monocyte chemoattractant protein 1, monocyte chemoattractant protein-1, SCYA2HSMCR30, small inducible cytokine A2 (monocyte chemotactic protein 1, homologous tomouse Sig-je), small inducible cytokine subfamily A (Cys-Cys), member 2, SMC-CF

Gene Symbol

CCL2

Additional CCL2/MCP1 Products

Product Documents for CCL2/MCP1 Antibody [DyLight 650]

Product Datasheets

Download Product Datasheets

COA

SDS

Product Specific Notices for CCL2/MCP1 Antibody [DyLight 650]

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews