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CCNDBP1 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-58940

Novus Biologicals, part of Bio-Techne
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NBP2-58940
NBP2-58940-25ul

Key Product Details

Species Reactivity

Validated:

Human

Applications

Immunocytochemistry/ Immunofluorescence, Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Product Summary for CCNDBP1 Antibody

Immunogen

This antibody was developed against a recombinant protein corresponding to the following amino acid sequence: SPENNDLISYNSVWVACQQMPQIPRDNKAAALLMLTKNVDFVKDAHEEMEQAVEECDPYSGLLNDTEENNSDNHNHEDDVLGFPSNQD

Reactivity Notes

Mouse 81%

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CCNDBP1 Antibody

Western Blot: CCNDBP1 Antibody [NBP2-58940]

Western Blot: CCNDBP1 Antibody [NBP2-58940]

Western Blot: CCNDBP1 Antibody [NBP2-58940] - Western blot analysis in human cell line RT-4.
Immunocytochemistry/ Immunofluorescence: CCNDBP1 Antibody [NBP2-58940]

Immunocytochemistry/ Immunofluorescence: CCNDBP1 Antibody [NBP2-58940]

Immunocytochemistry/Immunofluorescence: CCNDBP1 Antibody [NBP2-58940] - Staining of human cell line A-431 shows localization to nucleoplasm.

Applications for CCNDBP1 Antibody

Application
Recommended Usage

Immunocytochemistry/ Immunofluorescence

0.25-2 ug/ml

Western Blot

0.04-0.4 ug/ml
Application Notes
ICC/IF, Fixation Permeabilization: Use PFA/Triton X-100.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCNDBP1

CCNDBP1 was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Two alternatively spliced variants, which encode distinct isoforms, have been reported.

Alternate Names

cyclin D-type binding-protein 1, cyclin-D1-binding protein 1, DIP1HHM Protein, D-type cyclin-interacting protein 1, GCIPgrap2 cyclin interacting protein, Grap2 and cyclin-D-interacting protein, HHM, Human homolog of Maid, MAID protein

Gene Symbol

CCNDBP1

Additional CCNDBP1 Products

Product Documents for CCNDBP1 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCNDBP1 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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