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CCR3 Antibody (8E9H10) - BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-61672

Novus Biologicals, part of Bio-Techne
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NBP2-61672
NBP2-61672-0.025ml

Key Product Details

Species Reactivity

Validated:

Human

Applications

ELISA, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 8E9H10

Format

BSA Free

Concentration

1 mg/ml

Product Summary for CCR3 Antibody (8E9H10) - BSA Free

Immunogen

Purified recombinant fragment of human CCR3 (AA: extra mix) expressed in E. Coli.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Theoretical MW

41 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Scientific Data Images for CCR3 Antibody (8E9H10) - BSA Free

Western Blot: CCR3 Antibody (8E9H10)BSA Free [NBP2-61672]

Western Blot: CCR3 Antibody (8E9H10)BSA Free [NBP2-61672]

Western Blot: CCR3 Antibody (8E9H10) [NBP2-61672] - Analysis using CD193 mAb against human CD193 (AA: extra mix) recombinant protein. (Expected MW is 37.2 kDa)
Flow Cytometry: CCR3 Antibody (8E9H10) - BSA Free [NBP2-61672]

Flow Cytometry: CCR3 Antibody (8E9H10) - BSA Free [NBP2-61672]

Flow Cytometry: CCR3 Antibody (8E9H10) [NBP2-61672] - Analysis of K562 cells using CCR3 mouse mAb (green) and negative control (red).
Western Blot: CCR3 Antibody (8E9H10)BSA Free [NBP2-61672]

Western Blot: CCR3 Antibody (8E9H10)BSA Free [NBP2-61672]

Western Blot: CCR3 Antibody (8E9H10) [NBP2-61672] - Analysis using CD193 mAb against HEK293 (1) and CD193 (AA: extra mix)-hIgGFc transfected HEK293 (2) cell lysate.

Applications for CCR3 Antibody (8E9H10) - BSA Free

Application
Recommended Usage

ELISA

1:100-1:2000

Flow Cytometry

1:10-1:1000

Western Blot

1:100-1:2000
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Formulation

PBS

Format

BSA Free

Preservative

0.05% Sodium Azide

Concentration

1 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CCR3

The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

Alternate Names

CCR3, CD193

Gene Symbol

CCR3

Additional CCR3 Products

Product Documents for CCR3 Antibody (8E9H10) - BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCR3 Antibody (8E9H10) - BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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