CCR4 Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NB100-717

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
Qty
NB100-717-0.025mg
Print Quote
Bulk Order
100% Guarantee

Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human

Applications

Validated:

ELISA, Flow Cytometry, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen, Immunohistochemistry-Paraffin, Western Blot

Cited:

Flow Cytometry, IF/IHC, Immunocytochemistry/ Immunofluorescence, Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG

Concentration

1.0 mg/ml

View all CCR4 Antibodies »

Product Specifications

Immunogen

A synthetic peptide [SNYYLYESIPKPCTKEGIKAFGE] corresponding to amino acids 17-39 of the extracellular domain of human CCR4.

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Mouse, Monkey.

Localization

Cell membrane

Specificity

Peptide sequence is < 50 % identical to other human chemokine receptors in this region.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Scientific Data Images for CCR4 Antibody

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717]

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717]

Immunohistochemistry-Paraffin: CCR4 Antibody [NB100-717] - Section of human spleen.

Applications for CCR4 Antibody

Application
Recommended Usage

ELISA

1:30000

Flow Cytometry

1:12

Immunocytochemistry/ Immunofluorescence

1:400

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunohistochemistry-Paraffin

1:200

Western Blot

1:500
Application Notes
ICC/IF, IHC-F reactivity reported in (PMID: 23664188). Flow reactivity reported in (PMID: 15969628).

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

10mM KHPO4, 0.14M NaCl and 1.0 mg/ml BSA.

Preservative

0.1% Sodium Azide

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CCR4

Chemokine receptors are G protein-coupled receptors (GPCRs) that play a key role in inflammation and are characterized by similar sequences with a 4 cysteine motif. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen.

Alternate Names

CD194

Entrez Gene IDs

1233 (Human)

Gene Symbol

CCR4

UniProt

P51679

Additional CCR4 Products

Product Documents for CCR4 Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CCR4 Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Privacy and Cookie Policy
Site Map
© Copyright 2024 Bio-Techne. All Rights Reserved.