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CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-28362MFV450

Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Chicken

Applications

Flow Cytometry

Label

mFluor Violet 450 SE (Excitation = 406 nm, Emission = 445 nm)

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # CB3

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Specifications

Immunogen

Lymphocytes from the bursa of Fabricius of outbred chickens

Specificity

Chicken CD1.1

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Scientific Data Images for CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE]

CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE] [NBP1-28362MFV450] -

CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE] [NBP1-28362MFV450] - Vial of mFluor Violet 450 conjugated antibody. mFluor Violet 450 is optimally excited at 406 nm by the Violet laser (405 nm) and has an emission maximum of 445 nm.

Applications for CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE]

Application
Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD1.1 antigen

CD1 molecules, like MHC I and II, play an equally important role in the immune system by presenting lipid, glycolipid and lipopeptide antigen to T and NKT cells. (1) Chicken CD1 gene is located in the chicken MHC B locus and has an important implication for the primordial MHC gene evolution. (2) Two proteins have been identified: CD1.1 and CD1.2. Analysis of RNA from blood cells showed that both genes are expressed in Bu-1+ cells (B cells and some macrophages) and CD8a+ cells (some T and NK cells). CD1.2 is expressed in TCR1 + cells (gamma delta cells) but is nearly undetectable in TCR2+ and TCR3+ cells (alpha and Beta T cells)1. Clone CB3 antibody can identify cells of the B cell lineage and recognizes CD1.1 but not CD1.2 on the surface of transfected mammalian cells. (1)

Alternate Names

CD1, CD1a antigen, CD1A antigen, a polypeptide, CD1a molecule, cluster of differentiation 1 A, cortical thymocyte antigen CD1A, differentiation antigen CD1-alpha-3, epidermal dendritic cell marker CD1a, FCB6, HTA1, hTa1 thymocyte antigen, R4, T6, T-cell surface antigen T6/Leu-6, T-cell surface glycoprotein CD1a

Gene Symbol

CD1A

Additional CD1.1 antigen Products

Product Documents for CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD1.1 antigen Antibody (CB3) [mFluor Violet 450 SE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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