CD117/c-kit Antibody (351)

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-90037

Recombinant Monoclonal Antibody
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Human

Applications

ELISA, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # 351

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

View all CD117/c-kit Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human CD117/c-kit (Uniprot#: P10721-2; Met1-Thr516).

Specificity

No cross-reactivity in ELISA with: Mouse KITHuman PDGFRaHuman PDGFRb

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for CD117/c-kit Antibody (351)

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037] - Staining of human c-KIT in human breast cancer with rabbit monoclonal antibody (1:300).
Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037] - Staining of human c-KIT in human melanoma with rabbit monoclonal antibody (1:300).
Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037]

Immunohistochemistry-Paraffin: CD117/c-kit Antibody (351) [NBP2-90037] - Staining of human c-KIT in human skin with rabbit monoclonal antibody (1:300).

Applications for CD117/c-kit Antibody (351)

Application
Recommended Usage

ELISA

1:5000-1:10000

Immunohistochemistry-Paraffin

1:100-1:500

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD117/c-kit

CD117 is a 145 kD immunoglobulin superfamily member, also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with it's ligand is critical for the development of hematopoietic stem cells. The 2B8 antibody does not block c-Kit activity.

Long Name

Stem Cell Factor Receptor

Alternate Names

c-kit, CD117, ckit, KIT, PBT, SCF R, SCFR

Gene Symbol

KIT

Additional CD117/c-kit Products

Product Documents for CD117/c-kit Antibody (351)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Download SDS

Product Specific Notices for CD117/c-kit Antibody (351)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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