CD11c Antibody (CA11.6A1)

Novus Biologicals, part of Bio-Techne | Catalog # NB100-65291

Novus Biologicals, part of Bio-Techne
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NB100-65291
NB100-65291-0.25ml
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Key Product Details

Species Reactivity

Canine

Applications

Flow Cytometry, Immunohistochemistry, Immunohistochemistry-Frozen, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # CA11.6A1

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

View all CD11c Antibodies »

Product Specifications

Immunogen

Made to Dog CD11c

Reactivity Notes

Predicted cross-reactivities: Hooded Seal, Raccoon

Specificity

Recognizes the canine CD11c cell surface antigen, a member of the alpha integrin family. Canine CD11c is expressed by monocytes, granulocytes and by dendritic cells.

Marker

Dendritic Cell Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CD11c Antibody (CA11.6A1)

Flow Cytometry: CD11c Antibody (CA11.6A1) [NB100-65291]

Flow Cytometry: CD11c Antibody (CA11.6A1) [NB100-65291]

Flow Cytometry: CD11c Antibody (CA11.6A1) [NB100-65291] - Figure A. PE conjugated Mouse anti Canine CD45 and purified Mouse IgG1 isotype control detected with Goat anti Mouse IgG1 DyLight 649. Figure B. FITC conjugated Mouse anti Canine CD45 and purified Mouse anti Canine CD11c detected with Goat anti Mouse IgG1 DyLight 649. All experiments performed on red cell lysed canine blood gated on monocytes.

Applications for CD11c Antibody (CA11.6A1)

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500

Immunoprecipitation

1:10-1:500
Application Notes
The epitope recognised by this antibody is reported to be sensitive to formaldehyde fixation and tissue processing. The use of acetone fixation for frozen sections is recommended.

Reviewed Applications

Read 1 review rated 2 using NB100-65291 in the following applications:

Formulation, Preparation, and Storage

Purification

Tissue culture supernatant

Formulation

Tissue culture supernatant

Preservative

0.1% Sodium Azide

Concentration

This product is unpurified. The exact concentration of antibody is not quantifiable.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD11c

CD11c (integrin alpha X chain protein) combines with the beta 2 chain (ITGB2) to form a leukocyte specific integrin referred to as inactivated C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. The CD11c antigen is a marker for hairy cell leukemia.

Alternate Names

CD11c, Integrin alpha X, ITGAX, p150,95 alpha

Gene Symbol

ITGAX

Additional CD11c Products

Product Documents for CD11c Antibody (CA11.6A1)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD11c Antibody (CA11.6A1)

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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