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CD14 Antibody (50008) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # MAB38331

Novus Biologicals, part of Bio-Techne
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MAB38331
MAB38331-SP

Key Product Details

Species Reactivity

Human

Applications

Block/Neutralize, Simple Western

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 50008

Format

Azide and BSA Free

Concentration

1.0 mg/ml

Product Specifications

Immunogen

Partial recombinant human CD14 protein (amino acids 20-352)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Description

>90% by SDS PAGE

Applications for CD14 Antibody (50008) - Azide and BSA Free

Application
Recommended Usage

Simple Western

50 ug/ml
Application Notes
See Simple Western Antibody Database for Simple Western validation: tested in THP-1 cell line; separated by size; antibody dilution of 50 ug/ml; detects a band at 64 kDa.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

1.0 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CD14

CD14 is a 53-55 kD glycosylphosphatidylinositol (GPI)-linked membrane glycoprotein also known as LPS receptor. CD14 is expressed at high levels on monocytes and macrophages, and at lower levels on granulocytes. Some dendritic cell populations such as interfollicular dendritic cells, reticular dendritic cells, and Langerhans cells have also been reported to express CD14. As a high-affinity receptor for LPS, CD14 is involved in the clearance of gram-negative pathogens and in the upregulation of adhesion molecules and cytokines expression in monocytes and neutrophils. The M5E2 antibody inhibits monocyte activation and cytokine production induced by LPS.

Alternate Names

CD14

Gene Symbol

CD14

Additional CD14 Products

Product Documents for CD14 Antibody (50008) - Azide and BSA Free

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD14 Antibody (50008) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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