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CD1c/BDCA-1 Antibody (L161) [Janelia Fluor® 585]

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-62220JF585

Clone L161 was used by HLDA to establish CD designation.
Novus Biologicals, part of Bio-Techne

Key Product Details

Species Reactivity

Validated:

Human

Applications

Flow (Cell Surface), Flow Cytometry, Immunohistochemistry, Immunoprecipitation

Label

Janelia Fluor 585

Antibody Source

Monoclonal Mouse IgG1 kappa Clone # L161

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Product Summary for CD1c/BDCA-1 Antibody (L161) [Janelia Fluor® 585]

Immunogen

human thymocytes

Specificity

The antibody MEM-97 reacts with CD20 (Bp35), a 33-37 kDa non-glycosylated membrane receptor with four transmembrane domains, expressed on B lymphocytes (it is lost on plasma cells), follicular dendritic cells, and at low levels on peripheral blood T lymphocytes.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1 kappa

Applications for CD1c/BDCA-1 Antibody (L161) [Janelia Fluor® 585]

Application
Recommended Usage

Flow (Cell Surface)

Optimal dilutions of this antibody should be experimentally determined.

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunoprecipitation

Optimal dilutions of this antibody should be experimentally determined.
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

50mM Sodium Borate

Preservative

0.05% Sodium Azide

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD1c/BDCA-1

All CD1 molecules, except CD1e, are cell surface glycoproteins that are structurally related to the MHC molecules, however, in distinction, CD1 proteins are essentially non polymorphic. CD1 has considerable structural homology with both MHC class I and class II molecules, and CD1 molecules are involved in T cell activation. In contrast to MHC, however, CD1 molecules appear to present predominantly non peptide molecules originating from lipids and glycolipids.

Alternate Names

BDCA-1, BDCA1, CD1c, R7

Gene Symbol

CD1C

Additional CD1c/BDCA-1 Products

Product Documents for CD1c/BDCA-1 Antibody (L161) [Janelia Fluor® 585]

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

Product Specific Notices for CD1c/BDCA-1 Antibody (L161) [Janelia Fluor® 585]



Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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