CD21 Antibody (7D6)

Novus Biologicals, part of Bio-Techne | Catalog # DDX0120P-100

Novus Biologicals, part of Bio-Techne
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Key Product Details

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Frozen

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 7D6

Concentration

0.5 mg/ml

View all CD21 Antibodies »

Product Specifications

Immunogen

CD21 long isoform was used as immunogen.

Marker

Histiocytic Marker

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CD21 Antibody (7D6)

Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100]

Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100]

Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100] - mAb 7D6 staining on FDC clusters. Slides were incubated with mAb 7D6 and subsequently with a sheep anti-mouse IgG1. The binding of antibody was revealed using APAAP method and developed by Fast red substrate.
Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100]

Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100]

Immunohistochemistry: CD21 Antibody (7D6) [DDX0120P-100] - Giemsa staining of isolated FDCs clusters

Applications for CD21 Antibody (7D6)

Application
Recommended Usage

Immunohistochemistry

1:10-1:500

Immunohistochemistry-Frozen

1:10-1:500
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Ion exchange chromatography

Formulation

Tris-NaCl (pH 8.0)

Preservative

No Preservative

Concentration

0.5 mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at -20C. Avoid freeze-thaw cycles.

Background: CD21

CD21 (complement receptor 2, CR2) binds C3 complement fragments, especially its breakdown fragments, which remain covalently attached to complement activating surfaces or antigen. CD21 has important roles in uptake and retention of immunocomplexes, survival of memory B cells and in development and maintenance of the humoral response to T-dependent antigens. CD21 also serves as a key receptor for Epstein-Barr virus binding and is involved in targeting prions to folicular dendritic cells and expediting neuroinvasion following peripheral exposure to prions. A soluble form of the CD21 (sCD21) is shed from the lymphocyte surface and retains its ability to bind respective ligands.

Alternate Names

C3DR, CD21, CR2

Gene Symbol

CR2

Additional CD21 Products

Product Documents for CD21 Antibody (7D6)

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD21 Antibody (7D6)

This product is manufactured by Eurobio Scientific (formerly Dendritics) and distributed by Novus Biologicals.

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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