CD23/Fc epsilon RII Antibody (EBVCS2) [PE] [NBP1-43433PE] - Vial of PE conjugated antibody. PE has two excitation maxima, 498 nm excited by the Blue laser (488 nm) and 565 nm excited by the Yellow-Green laser (561 nm). Both result in emission at 578 nm.

Applications for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Application

Recommended Usage

Flow Cytometry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Frozen

Optimal dilutions of this antibody should be experimentally determined.

Immunohistochemistry-Paraffin

Optimal dilutions of this antibody should be experimentally determined.

Application Notes

Optimal dilution of this antibody should be experimentally determined.

Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A or G purified

Formulation

PBS

Preservative

0.05% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C in the dark.

Background: CD23/Fc epsilon RII

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a

Long Name

Fc epsilon Receptor II

Alternate Names

CD23, CLEC4J, Fc epsilon RII, FCER2, Fcer2a, FceRII, IGEBF, Ly-42

Gene Symbol

FCER2

Additional CD23/Fc epsilon RII Products

Product Documents for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Product Datasheets

Download Product Datasheets

COA

SDS

Download SDS

Product Specific Notices for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Citations
Reviews

Spectra Viewer
Flow Cytometry

CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Novus Biologicals, part of Bio-Techne | Catalog # NBP1-43433PE

Key Product Details

Species Reactivity

Validated:

Applications

Label

Antibody Source

Concentration

View all CD23/Fc epsilon RII Antibodies »

Product Summary for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Immunogen

Clonality

Host

Isotype

Scientific Data Images for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

CD23/Fc epsilon RII Antibody (EBVCS2) [PE] [NBP1-43433PE] -

Applications for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Flow Cytometry

Immunohistochemistry

Immunohistochemistry-Frozen

Immunohistochemistry-Paraffin

Formulation, Preparation, and Storage

Purification

Formulation

Preservative

Concentration

Shipping

Stability & Storage

Background: CD23/Fc epsilon RII

Long Name

Alternate Names

Gene Symbol

Additional CD23/Fc epsilon RII Products

Product Documents for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]

Product Datasheets

COA

Certificate of Analysis

SDS

Product Specific Notices for CD23/Fc epsilon RII Antibody (EBVCS2) [PE]