CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-12152

Novus Biologicals, part of Bio-Techne
Catalog #
Availability
Size / Price
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NBP2-12152
NBP2-12152-0.025mg
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Conjugate
Catalog #
Alexa Fluor 350
NBP2-12152AF350
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Alexa Fluor 405
NBP2-12152AF405
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Alexa Fluor 488
NBP2-12152AF488
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Alexa Fluor 532
NBP2-12152AF532
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Alexa Fluor 594
NBP2-12152AF594
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Alexa Fluor 647
NBP2-12152AF647
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Alexa Fluor 700
NBP2-12152AF700
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Alexa Fluor 750
NBP2-12152AF750
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Allophycocyanin
NBP2-12152APC
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Allophycocyanin/Cy7
NBP2-12152APCCY7
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Biotin
NBP2-12152B
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CoraFluor 1
NBP2-12152CL1
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DyLight 350
NBP2-12152UV
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DyLight 405
NBP2-12152V
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DyLight 488
NBP2-12152G
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DyLight 550
NBP2-12152R
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DyLight 594
NBP2-12152DL594
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DyLight 650
NBP2-12152C
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DyLight 680
NBP2-12152FR
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DyLight 755
NBP2-12152IR
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FITC
NBP2-12152F
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HRP
NBP2-12152H
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Janelia Fluor 525
NBP2-12152JF525
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Janelia Fluor 549
NBP2-12152JF549
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Janelia Fluor 585
NBP2-12152JF585
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Janelia Fluor 635
NBP2-12152JF635
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Janelia Fluor 646
NBP2-12152JF646
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Janelia Fluor 669
NBP2-12152JF669
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mFluor Violet 450 SE
NBP2-12152MFV450
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mFluor Violet 500 SE
NBP2-12152MFV500
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mFluor Violet 610 SE
NBP2-12152MFV610
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PE
NBP2-12152PE
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PE/Atto594
NBP2-12152PEATT594
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PE/Cy5.5
NBP2-12152PECY55
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PE/Cy7
NBP2-12152PECY7
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PerCP
NBP2-12152PCP
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Key Product Details

Species Reactivity

Validated:

Human

Applications

Block/Neutralize, CyTOF-ready, Flow Cytometry, Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # MM0164-2C23

Format

Azide and BSA Free

Concentration

LYOPH mg/ml

View all CD23/Fc epsilon RII Antibodies »

Product Summary for CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

Immunogen

Human recombinant CD23/Fc epsilon RII (extracellular domain)

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

Flow Cytometry: CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free [NBP2-12152]

Flow Cytometry: CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free [NBP2-12152]

Flow Cytometry: CD23/Fc epsilon RII Antibody (MM0164-2C23) [NBP2-12152] - Analysis using the DyLight 405 conjugate of NBP2-12152. Staining of CD23 in human PBMCs using anti-CD23 antibody. Image from verified customer review.

Applications for CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

Application
Recommended Usage

Flow Cytometry

1:10-1:1000

Western Blot

1:500-1:1000
Application Notes
This antibody is Cytof ready.
Please Note: Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein G purified

Reconstitution

Reconstitute with sterilized PBS to a final concentration of 0.5 mg/ml.

Formulation

Lyophilized from a 0.2 um filtered solution in PBS. 0.025 mg size is provided in liquid form, PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

LYOPH mg/ml

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD23/Fc epsilon RII

The CD23 antigen is the low affinity IgE Fc receptor, which is a 49 kDa protein with 38 and 28 kDa fragments. It is expressed on most mature, conventional B cells (but not on peritoneal CD5+ B cells), and can also be found on the surface of T cells, macrophages, platelets and EBV transformed B lymphoblasts. Expression of CD23 has been detected in neoplastic cells from cases of B cell chronic Lymphocytic leukemia. CD23 is expressed by B cells in the follicular mantle but not by proliferating germinal centre cells. CD23 is also expressed by eosinophils. CD23 is distinct from the high affinity IgE receptors found on basophils and mast cells, which mediate allergic reactions. The low affinity receptors are thought to play a role in isotype specific immunoregulation. The regulation of CD23 surface expression appears to be integral with the complex IgE system, which involves interactions of cells, cytokines, antibodies and regulatory factors. CD23 has been described as a

Long Name

Fc epsilon Receptor II

Alternate Names

CD23, CLEC4J, Fc epsilon RII, FCER2, Fcer2a, FceRII, IGEBF, Ly-42

Gene Symbol

FCER2

UniProt

P06734

Additional CD23/Fc epsilon RII Products

Product Documents for CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD23/Fc epsilon RII Antibody (MM0164-2C23) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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