CD25/IL-2R alpha Antibody

Novus Biologicals, part of Bio-Techne | Catalog # NBP2-38730

Novus Biologicals, part of Bio-Techne
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NBP2-38730-25ul
NBP2-38730
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Key Product Details

Validated by

Orthogonal Validation

Species Reactivity

Human

Applications

Immunohistochemistry, Immunohistochemistry-Paraffin

Label

Unconjugated

Antibody Source

Polyclonal Rabbit IgG

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

View all CD25/IL-2R alpha Antibodies »

Product Specifications

Immunogen

This antibody was developed against a recombinant protein corresponding to amino acids: YKEGTMLNCECKRGFRRIKSGSLYMLCTGNSSHSSWDNQCQCTSSATRNTTKQVTPQPEEQKERKTTEMQSPMQP

Clonality

Polyclonal

Host

Rabbit

Isotype

IgG

Scientific Data Images for CD25/IL-2R alpha Antibody

Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730] - CD25/IL-2 R alpha Antibody [NBP2-38730] - Analysis in human lymph node and cerebral cortex tissues. Corresponding IL2RA RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2 R alpha Antibody [NBP2-38730] - Staining of human lymph node shows strong membranous positivity in non-germinal center cells.
Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2R alpha Antibody [NBP2-38730]

Immunohistochemistry-Paraffin: CD25/IL-2 R alpha Antibody [NBP2-38730] - Staining of human cerebral cortex shows no positivity in neurons as expected.
View 2 more images

Applications for CD25/IL-2R alpha Antibody

Application
Recommended Usage

Immunohistochemistry

1:1000 - 1:2500

Immunohistochemistry-Paraffin

1:1000 - 1:2500
Application Notes
For IHC-Paraffin, HIER pH 6 retrieval is recommended.

Formulation, Preparation, and Storage

Purification

Immunogen affinity purified

Formulation

PBS (pH 7.2) and 40% Glycerol

Preservative

0.02% Sodium Azide

Concentration

Concentrations vary lot to lot. See vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: CD25/IL-2R alpha

The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency.(provided by RefSeq)

Long Name

Interleukin 2 Receptor alpha

Alternate Names

CD25, IL-2 R alpha, IL-2Ra, IL2R alpha, IL2RA

Gene Symbol

IL2RA

UniProt

P01589

Additional CD25/IL-2R alpha Products

Product Documents for CD25/IL-2R alpha Antibody

Product Datasheets

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot number in the search box below.

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Product Specific Notices for CD25/IL-2R alpha Antibody

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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